Dr. Ger van Zandbergen
Institute for Medical Microbiology and Hygiene
University Hospital Ulm
Albert-Einstein-Allee 11, 89081 Ulm, Germany
Tel.: +49-(0)731/500-65370, Fax: +49(0)731/500-65328
|1989 - 1995|| |
Master degree:I. The use of Lactococcus lactis as a vaccine carrier: Expression of the CMV pp65 protein in L. lactis;
II. Selection of single chains (Fv) fragments against the tumor associated antigen EGP-1, using the “Nissim” phage display library.
University of Leiden and Utrecht, the Netherlands.
Interactions of IgA with the Fc Receptor CD89, ISBN 90-9013211-2, 1999, under supervision of Prof. M. R. Daha, Dr. C van Kooten and Prof. J. G.W. van de Winkel
|2000-2007 ||Post-doctoral fellow/principal investigator: |
University of Lübeck, Germany, Department of Medical Microbiology and Hygiene of Prof. W. Solbach in the group of Prof. T. Laskay.
Post doctoral projects:I. Leukocyte recruitment and local immune response in the pre-immune stage of murine infection with Leishmania major.
II. Opsonin independent recognition of intracellular pathogens by polymorphonuclear granulocytes (PMN) and secretion of immunomodelatory mediators by infected PMN.
III. The role of neutrophil granulocytes as target cells and transport vehicle for intracellular pathogens
|2007 -|| |
Research projects:Apoptosis driven infection: I. The role of parasitic phosphatidylserine in the infection of human polymorphonuclear neutrophil granulocytes (PMN) by Leishmania major. II. Apoptosis and parasitism: the example of infection with Leishmania spp. III. Lipid-mediated establishment of intracellular life in granulocytes. IV. Chlamydia pneumoniae uses apoptotic granulocytes to silently infect host macrophages. V. Chlamydia pneumoniae infection stage specific regulation of host cell survival.