Dr. Ger van Zandbergen


Institute for Medical Microbiology and Hygiene

University Hospital Ulm

Albert-Einstein-Allee 11, 89081 Ulm, Germany

Tel.: +49-(0)731/500-65370, Fax: +49(0)731/500-65328

E-mail: Ger.Zandbergen[at]uniklinik-ulm.de


Scientific career

1989 - 1995

University of Groningen, the Netherlands.

Master degree:

I. The use of Lactococcus lactis as a vaccine carrier: Expression of the CMV pp65 protein in L. lactis;
II. Selection of single chains (Fv) fragments against the tumor associated antigen EGP-1, using the “Nissim” phage display library.
University of Leiden and Utrecht, the Netherlands.

PhD thesis:
 Interactions of IgA with the Fc Receptor CD89, ISBN 90-9013211-2, 1999, under supervision of Prof. M. R. Daha, Dr. C van Kooten and Prof. J. G.W. van de Winkel
Post-doctoral fellow/principal investigator:
University of Lübeck, Germany, Department of Medical Microbiology and Hygiene of Prof. W. Solbach in the group of Prof. T. Laskay.

Post doctoral projects:

I. Leukocyte recruitment and local immune response in the pre-immune stage of murine infection with Leishmania major.
Opsonin independent recognition of intracellular pathogens by polymorphonuclear granulocytes (PMN) and secretion of immunomodelatory mediators by infected PMN.
III. The role of neutrophil granulocytes as target cells and transport vehicle for intracellular pathogens
2007 -

Principal investigator:
University of Ulm, Germany, Department of Medical Microbiology and Hygiene of Prof. S. Stenger

Research projects:

Apoptosis driven infection: I. The role of parasitic phosphatidylserine in the infection of human polymorphonuclear neutrophil granulocytes (PMN) by Leishmania major. II. Apoptosis and parasitism: the example of infection with Leishmania spp. III. Lipid-mediated establishment of intracellular life in granulocytes. IV. Chlamydia pneumoniae uses apoptotic granulocytes to silently infect host macrophages. V. Chlamydia pneumoniae infection stage specific regulation of host cell survival.

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