Veröffentlichungen

2010

Hypoxia abrogates antichlamydial properties of IFN-{gamma} in human fallopian tube cells in vitro and ex vivo.

Roth A, König P, van Zandbergen G, Klinger M, Hellwig-Bürgel T, Däubener W, Bohlmann MK, Rupp J.

Proc Natl Acad Sci U S A. 2010 Nov 9;107(45):19502-7. Epub 2010 Oct 25.PMID: 20974954 [PubMed - in process]Related citations

Programmed cell death in unicellular parasites: a prerequisite for sustained infection?

van Zandbergen G, Lüder CG, Heussler V, Duszenko M.

Trends Parasitol. 2010 Oct;26(10):477-83. Epub 2010 Jun 28.PMID: 20591738 [PubMed - in process]Related citations

The C2-streptavidin delivery system promotes the uptake of biotinylated molecules in macrophages and T-leukemia cells.

Fahrer J, Rieger J, van Zandbergen G, Barth H.

Biol Chem. 2010 Sep 24. [Epub ahead of print]PMID: 20868225 [PubMed - as supplied by publisher]Related citations


Deletion of UDP-glucose pyrophosphorylase reveals a UDP-glucose independent UDP-galactose salvage pathway in Leishmania major.

Lamerz AC, Damerow S, Kleczka B, Wiese M, van Zandbergen G, Lamerz J, Wenzel A, Hsu FF, Turk J, Beverley SM, Routier FH.

Glycobiology. 2010 Jul;20(7):872-82. Epub 2010 Mar 24.

Phagocytosis of apoptotic cells by neutrophil granulocytes: diminished proinflammatory neutrophil functions in the presence of apoptotic cells.

Esmann L, Idel C, Sarkar A, Hellberg L, Behnen M, Möller S, van Zandbergen G, Klinger M, Köhl J, Bussmeyer U, Solbach W, Laskay T.

J Immunol. 2010 Jan 1;184(1):391-400. Epub 2009 Nov 30.

Impairment of gamma interferon signaling in human neutrophils infected with Anaplasma phagocytophilum.

Bussmeyer U, Sarkar A, Broszat K, Lüdemann T, Möller S, van Zandbergen G, Bogdan C, Behnen M, Dumler JS, von Loewenich FD, Solbach W, Laskay T.

Infect Immun. 2010 Jan;78(1):358-63. Epub 2009 Oct 26.

2009

Lipoxin A4 receptor dependent leishmania infection.

Wenzel A, Van Zandbergen G.

Autoimmunity. 2009 May;42(4):331-3.

Are neutrophils important host cells for Leishmania parasites?

Ritter U, Frischknecht F, van Zandbergen G.

Trends Parasitol. 2009 Nov;25(11):505-10. Epub 2009 Sep 15.

Chlamydia pneumoniae hides inside apoptotic neutrophils to silently infect and propagate in macrophages.

Rupp J, Pfleiderer L, Jugert C, Moeller S, Klinger M, Dalhoff K, Solbach W, Stenger S, Laskay T, van Zandbergen G.

PLoS One. 2009 Jun 23;4(6):e6020.

2008

Neutrophil granulocytes as host cells and transport vehicles for intracellular pathogens: apoptosis as infection-promoting factor.

Laskay T, van Zandbergen G, Solbach W.

Immunobiology. 2008;213(3-4):183-91. Epub 2008 Feb 8. Review.

2007

van Zandbergen, G., Solbach, W. and Laskay, T. 2007 Apoptosis driven infection., Invited review for Autoimmunity: special issue on uptake of apoptotic cells., 40(4):349-52


Rupp, J., Gieffers, J., Klinger, M., van Zandbergen, G., Wrase, R., Maas, M., Solbach, W., Deiwick and  J., Hellwig-Burgel, T. 2007 Chlamydia pneumoniae directly interferes with HIF-1α stabilization in human host cells. Cell. Microbiol. (9):2181-91


Kleczka, B., Lamerz, A., van Zandbergen, G., Wenzel, A., Gerardy-Schahn, R., Wiese, M., and Routier, F.H. 2007 Targeted gene deletion of Leishmania major UDP-galactopyranose mutase leads to attenuated virulence. J. Biol. Chem. 282(14):10498-505

2006

van Zandbergen, G., Bollinger, A., Wenzel, A., Kamhawi, S., Voll, R., Klinger, M., Müller, A., Hölscher, C., Herrmann, M., Sacks, D., Solbach, W. and Laskay, T. 2006. Apoptotic Leishmania promastigotes in the virulent inoculum enable disease development. Proc. Natl. Acad. Sci. U S A. 103(37):13837-42


Wilde, I., Lotz, S., Engelmann, D., Starke, A., van Zandbergen, G., Solbach, W., Laskay, T., 2006 Direct stimulatory effects of the TLR2/6 ligand bacterial lipopeptide MALP-2 on neutrophil granulocytes. Med Microbiol Immunol., DOI 10.1007/s00430-006-0027-9

2005

Rupp, J., M. Koch, G. van Zandbergen, W. Solbach, E. Brandt, and M. Maass. 2005. Transmission of Chlamydia pneumoniae infection from blood monocytes to vascular cells in a novel transendothelial migration model. FEMS microbiol. let., 242:203-208

2004

van Zandbergen, G., M. Klinger, A. Müller, A. Gebert, W. Solbach, and T. Laskay. 2004. Cutting edge: Neutrophil granulocyte serves as a vector for leishmania entry into macrophages. J. Immunol., 173:6521-6525


Strassburg, A., D. Droemann, G. van Zandbergen, H. Kothe, and K. Dalhoff. 2004. Enhanced PMN response in chronic bronchitis and community-acquired pneumonia. Eur. Respir. J. 24:772-778


van der Boog, P. J., C. van Kooten, G. van Zandbergen, N. Klar-Mohamad, B. Oortwijn, N. A. Bos, van Remoortere A., C. H. Hokke, J. W. de Fijter, and M. R. Daha. 2004. Injection of recombinant Fc{alpha}RI/CD89 in mice does not induce mesangial IgA deposition. Nephrol. Dial. Transplant. 19:2729-2736


Gieffers, J., G. van Zandbergen, J. Rupp, F. Sayk, S. Krüger, S. Ehlers, W. Solbach, and M. Maass. 2004. Phagocytes transmit Chlamydia pneumoniae from the lungs to the vasculature. Eur. Respir. J. 23:506-510


van Zandbergen, G., J. Gieffers, H. Kothe, J. Rupp, A. Bollinger, E. Aga, M. Klinger, H. Brade, K. Dalhoff, M. Maass, W. Solbach, and T. Laskay. 2004. Chlamydia pneumoniae multiply in neutrophil granulocytes and delay their spontaneous apoptosis. J. Immunol. 172:1768-1776


Lotz, S., E. Aga, I. Wilde, G. van Zandbergen, T. Hartung, W. Solbach, and T. Laskay. 2004. Highly purified lipoteichoic acid activates neutrophil granulocytes and delays their spontaneous apoptosis via CD14 and TLR2. J. Leukoc. Biol. 75:467-477.

2003

Schultz, H., H. Heintz, G. van Zandbergen, S. Ullrich, E. Reinhold-Keller, and W. L. Gross. 2003. ANCA against the bactericidal/permeability increasing protein (BPI-ANCA) can compromise the antibiotic function of BPI in a Wegener's granulomatosis patient. Clin. Exp. Rheumatol. 21:763-766


Laskay, T., G. van Zandbergen, and W. Solbach. 2003. Neutrophil granulocytes--Trojan horses for Leishmania major and other intracellular microbes? Trends Microbiol. 11:210-214

2002

van Zandbergen, G., N. Hermann, H. Laufs, W. Solbach, and T. Laskay. 2002. Leishmania promastigotes release a granulocyte chemotactic factor and induce interleukin-8 release but inhibit gamma interferon-inducible protein 10 production by neutrophil granulocytes. Infect. Immun. 70:4177-4184


Aga, E., D. M. Katschinski, G. van Zandbergen, H. Laufs, B. Hansen, K. Müller, W. Solbach, and T. Laskay. 2002. Inhibition of the spontaneous apoptosis of neutrophil granulocytes by the intracellular parasite Leishmania major. J. Immunol. 169:898-905


Kreft, B., W. J. Jabs, T. Laskay, M. Klinger, W. Solbach, S. Kumar, and G. van Zandbergen. 2002. Polarized expression of Tamm-Horsfall protein by renal tubular epithelial cells activates human granulocytes. Infect. Immun. 70:2650-2656


van der Boog, P. J., van Zandbergen G., J. W. de Fijter, N. Klar-Mohamad, A. van Seggelen, P. Brandtzaeg, M. R. Daha, and C. van Kooten. 2002. Fc alpha RI/CD89 circulates in human serum covalently linked to IgA in a polymeric state. J. Immunol. 168:1252-125

2001

Müller, K., G. van Zandbergen, B. Hansen, H. Laufs, N. Jahnke, W. Solbach, and T. Laskay. 2001. Chemokines, natural killer cells and granulocytes in the early course of Leishmania major infection in mice. Med. Microbiol. Immunol. (Berl) 190:73-76.

2000

van Egmond, M., E. van Garderen, A. B. van Spriel, C. A. Damen, E. S. van Amersfoort, G. van Zandbergen, J. van Hattum, J. Kuiper, and J. G. van de Winkel. 2000. FcalphaRI-positive liver Kupffer cells: reappraisal of the function of immunoglobulin A in immunity. Nat. Med. 6:680-685.

1999

van Zandbergen, G., R. Westerhuis, N. K. Mohamad, J. G. van de Winkel, M. R. Daha, and C. van Kooten. 1999. Crosslinking of the human Fc receptor for IgA (FcalphaRI/CD89) triggers FcR gamma-chain-dependent shedding of soluble CD89. J. Immunol. 163:5806-5812


Morton, H. C., G. van Zandbergen, C. van Kooten, C. J. Howard, J. G. van de Winkel, and P. Brandtzaeg. 1999. Immunoglobulin-binding sites of human FcalphaRI (CD89) and bovine Fcgamma2R are located in their membrane-distal extracellular domains. J. Exp. Med. 189:1715-1722


van Zandbergen, G., R. Westerhuis, N. A. Verhagen, N. Klar-Mohamad, M. R. Daha, and C. van Kooten. 1999. Human mesangial cells in culture and in kidney sections fail to express Fc alpha receptor (CD89). J. Am. Soc. Nephrol. 10:770-778

1998

van Zandbergen, G., C. van Kooten, N. K. Mohamad, T. J. Reterink, J. W. de Fijter, J. G. van de Winkel, and M. R. Daha. 1998. Reduced binding of immunoglobulin A (IgA) from patients with primary IgA nephropathy to the myeloid IgA Fc-receptor, CD89. Nephrol. Dial. Transplant. 13:3058-3064

1997

Reterink, T. J., G. van Zandbergen, M. van Egmond, N. Klar-Mohamad, C. H. Morton, J. G. van de Winkel, and M. R. Daha. 1997. Size-dependent effect of IgA on the IgA Fc receptor (CD89). Eur. J. Immunol. 27:2219-2224

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