Originalarbeiten

 

1. M. Karl, G. von Wichert, E. Kempter, D.A. Katz, M. Reincke, H. Mönig, I.U. Ali, C.A. Stratakis, E.H. Oldfield, G.P. Chrousos and H.M. Schulte Nelson's syndrome associated with a somatic frame shift mutation in the glucocorticoid receptor gene 1996, J. Clin. Endocrinol Metab. 81: 124-9

 

2. G. von Wichert, P.M. Jehle, A. Hoeflich, S. Koschnick, H. Dralle, E. Wolf, B. Wiedenmann, B.O. Boehm, Guido Adler and Thomas Seufferlein, Insulin-like growth factor-I is an autocrine regulator of chromogranin A secretion and growth in human neuroendocrine tumor cells 2000, Cancer Res. 60: 4573-81

 

3. T. Seufferlein, M.J. Seckl, E. Schwarz, M. Beil, G. von Wichert, H. Baust, H. Lührs, R.M. Schmid and G. Adler Mechanisms of nordihydroguaiaretic acid-induced growth inhibition and apoptosis in human cancer cells 2002, Br. J. Cancer 86: 1188-96

 

4. G. von Wichert, G. Jiang, A. Kostic, K. De Vos, J. Sap and M.P. Sheetz, RPTP-alpha acts as a transducer of mechanical force on alpha_v/ß₃-integrin-cytoskeleton linkages 2003, J. Cell Biol. 161: 143-153

 

5. M. Beil, A. Micoulet, G. von Wichert, S. Paschke, P. Walter, B. Omary, P. van Veldhoven, U. Gern, E. Wolff-Hieber, J. Eggermann, J. Waltenberger, G. Adler, J. Spatz  and T. Seufferlein, Shingosylphosphorylcholine regulates the keratin cytoskeleton and cellular viscoelasticity of human eithelial tumor cells 2003, Nat. Cell Biol. 9: 803-11

 

6. G. von Wichert, G.S. Feng and M.P. Sheetz, Force dependent establishment of integrin-cytoskeleton linkages requires downregulation of focal contact dynamics by Shp2 2003, Embo J. 22: 5023-35

 

7. G. von Wichert, U. Haeussler, F.R. Greten, S. Kliche, H. Dralle, B.O. Böhm, G. Adler and T. Seufferlein, Regulation of cyclin D1 expression by autocrine IGF-I in human BON neuroendocrine tumor cells 2005, Oncogene 24:1284-89

 

8. U. Haeussler, G. von Wichert, R. M. Schmid, F. Keller and G. Schneider, Epidermal Growth Factor (EGF) activates nuclear factor B in human proximal tubule cells 2005, Am. J. Physiol. renal, 289: 808-15

 

9. A. Auer, J. von Blume, S Sturany, G. von Wichert, J. van Lint, J. Vandenheede, G. Adler and T. Seufferlein Role of the regulatory domain of protein kinase D2 in phorbol ester binding, catalytic activity and nucleocytoplasmic shuttling 2005, Mol. Biol. Cell, 16:4375-85

 

10. G. von Wichert and M.P. Sheetz The biophysical interpretation of the ECM affects physiological and patho-physiological cellular behavior 2005; Z. Gastroenterol.,43:1329-1336

 

11. G. von Wichert und P. von Wichert Möglichkeiten und Probleme der Applikation von systemisch wirksamen, höhermolekularen Wirkstoffen mittels Inhalation 2006, Med. Klin: 101(9):718-23

 

12. K. Jungert, A. Buck, G. Adler, G. von Wichert, T. M. Gress, V. Ellenrieder Sp1 is required for TGFß induced transcriptional induction of mesenchymal transition and migration in pancreatic cancer cells 2007, Cancer Res: 67:1563-70

 

13. T Seufferlein, G. von Wichert, G Adler. Palliative treatment of pancreatic cancer Dtsch Med Wochenschr. 2007;132:813-7

 

14. T. Aleksic, G. von Wichert, K. Giehl, T.M. Gress, P. Michl CUTL1 promotes tumor cell migration by decreasing proteasome-mediated Src degradation 2007, Oncogene: 26(40):5939-49

 

15. B Baumann, M Wagner, T Aleksic, G. von Wichert, CK Weber, G Adler, T Wirth. Constitutive IKK2 activation in acinar cells is sufficient to induce pancreatitis in vivo. 2007, J Clin Invest: 117:1502-13.

 

16. T Seufferlein, G von Wichert, G Adler Medikamentöse Therapie des Kolonkarzinoms  Dtsch Med Wochenschr 2007: 132(38):1951-62

 

17. G von Wichert, T Seufferlein Adjuvante Chemotherapie bei soliden Tumoren des Gastrointestinaltraktes - sind Fortschritte erkennbar? Internist: 2007 48(12):1335-1342

 

18. T. Seufferlein, G. von Wichert, G. Adler Diagnostik und Therapie des Pankreaskarzinoms Pharma Fokus Onkologie. 2007: 4; 12: 2-5

 

19. G von Wichert, D Krndija, H Schmid, G von Wichert, G Haerter, G Adler, T Seufferlein, M P Sheetz Focal Adhesion Kinase mediates defects in the force-dependent reinforcement of initial integrin-cytoskeleton linkages in metastatic colon cancer cell lines 2008, E J Cell Biol: 87(1):1-16

 

20. G. von Wichert, T Seufferlein, G. Adler Palliative treatment of pancreatic cancer? 2008 J. Dig. Dis.: 9(1):1-7.

 

21. G von Wichert, G. Adler, T. Seufferlein Die Therapie des kolorektalen Karzinoms Tumordiagnostik & Therapie 2008, 03: (29); 134-139

 

22. G. von Wichert, T Edenfeld, J von Blume, H Krisp, D Krndija, H Schmid, F Oswald, P Walther, G Adler, T Seufferlein Protein kinase D2 regulates chromogranin A secretion in human BON neuroendocrine tumour cells 2008 Cell Signal: 20(5):925-34

 

23. G von Wichert,  G. Adler, T. Seufferlein Die Prävention des kolorektalen Karzinoms Tumordiagnostik & Therapie 2008, 03: (29); 128-132

 

24. V. Kächele, G. von Wichert, G. Adler, T Seufferlein Response to the reintroduction of cetuximab in patients with advanced, chemotherapy-resistant colorectal cancers without progress during first-line application of the antibody 2008, Oncology 74:123-126.

 

25. T. Seufferlein, J. Ahn, D. Krndija, U. Lother, G. Adler, G. von Wichert Tumor biology and cancer therapy - an evolving relationship. Cell Commun Signal. 2009 13; 7:19.

 

26. S. Walter, G. Adler, G von Wichert Kolonkarzinom: Einfluss der Ernährung  sowie Prävention und Diagnostik Pharma Fokus Onkologie. 2009: 6; 12: 15-20

 

27. D Krndija, H Schmid, J Eismann, U Lother, G Adler, F Oswald, T Seufferlein, G von Wichert Substrate stiffness and the receptor-type tyrosine-protein phosphatase alpha (RPTPα) regulate spreading of colon cancer cells via cytoskeletal contractility 2010, Oncogene Epub, March 8

 

28. J. Stephani, G. Adler, G. von Wichert Aktuelle Therapie der Gicht Gastroenterologie up2date 2010 (6);1-16

 

29. G. V. Pusapati, D. Krndija, M. Armacki, G. von Wichert, J. von Blume, V. Malhotra, G. Adler, T. Seufferlein Role of the second cysteine-rich domain and Pro275 in PKD2 interaction with ARF1, TGN recruitment and protein transport 2010 Mol Biol Cell 21(6):1011-22

 

30. V. Kaechele, M Moehler, MP Lutz, G von Wichert, M Eisele, J Klaus, PR Galle, G Adler, T Seufferlein A phase I/II study of oxaliplatin and paclitaxel in patients with non-resectable cancer of the oesophagus and adenocarcinoma of the gastro oesophageal junction: A Study of the Arbeitsgemeinschaft Internistische Onkologie 2010 Cancer Chemother Pharmacol. 66(1):191-5

 

31. J. Huth, M. Buchholz, M. Schmucker, G. von Wichert, D. Krndija, T. Seufferlein, T.M. Gress, H. A. Kestler Cell migration analysis in time lapse imaging – automated vs manual tracking 2010 BMC Cell Biol.;11(1):24