Originalarbeiten

  1. R.W. Grunewald, M. Wagner, I. Schubert, H.E. Franz, G.A. Müller, J. Steffgen. Rat renal expression of mRNA coding for aldose reductase and sorbitol dehydrogenase and its osmotic regulation in inner medullary collecting duct cells. Cell Physiol Biochem 8:293-303 (1998)
  2. M. Wagner, H. Lührs, G. Klöppel, G. Adler, R.M. Schmid. Malignant transformation of duct-like cells originating from acini in transforming growth factor a transgenic mice. Gastroenterology 115:1254-62 (1998)
  3.  A.U. Steinle, H. Weidenbach, M. Wagner, G. Adler, R.M. Schmid. NF-kappaB/Rel activation in cerulein pancreatitis.  Gastroenterology 116:420-30 (1999)
  4. M.P. Ebert, J. Hoffmann, C. Häckel, K. Rutkowski, R.M. Schmid, M. Wagner, G. Adler, H.U. Schulz, A. Rössner, W. Hoffmann, P. Malfertheiner. Induction of TFF1 gene expression in pancreas overexpressing transforming growth factor alpha. Gut 45:105-111 (1999)
  5. Y. Tando, H. Algül, M. Wagner, H. Weidenbach, G. Adler, R.M. Schmid. Caerulein-induced NF-kappaB/Rel activation requires both Ca(2+) and protein kinase C as messengers. Am J Physiol 277: G678-G686 (1999)
  6. R.M. Schmid, G. Klöppel, G. Adler, M. Wagner. Acinar-ductal-carcinoma sequence in transforming growth factor-alpha transgenic mice. Ann N Y Acad Sci 880:219-30 (1999)
  7. M. Schwarz, F. Cecconi, G. Bernier, N. Andrejewski, B. Kammandel, M. Wagner, P. Gruss. Spatial specification of mammalian eye territories by reciprocal transcriptional repression of Pax2 and Pax6. Development 127: 4325-4334 (2000)
  8. V. Ellenrieder, B. Alber, U. Lacher, S. Hendler, A. Menke, W. Böck, M. Wagner, M. Wilda, H. Friess, M. Büchler, G. Adler, T. Gress. Role of MT-MMPs and MMP-2 in pancreatic cancer progression. Int J Cancer 85: 14-20 (2000)
  9. L. Ludwig, H. Kessler, M. Wagner, C. Hoang-Vu, H. Dralle, G. Adler, B.O. Böhm, R.M. Schmid. Nuclear factor-kappaB is constitutively active in c-cell carcinoma and required for ret-induced transformation. Cancer Res. 61: 4526-35 (2001)
  10. R. Vogelmann, D. Ruf, M. Wagner, G. Adler, A. Menke. Effects of fibrogenic mediators on the development of pancreatic fibrosis in a TGFb1 transgenic mouse model. Am J Physiol. 280: G164-G172 (2001)
  11. M. Wagner, U. Seitz, T.A. Vogg, G. Glatting, B. Neumaier, F.R. Greten, R.M. Schmid, S.N.Reske.In vivo evaluation of 5-[18F]Fluoro-2'-deoxyuridine as tracer for positron emission tomography in a murine pancreatic cancer model. Cancer Res 61: 3853-7 (2001) (gemeinsame Erstautorschaft mit U. Seitz)
  12. M. Wagner, F.R. Greten, C.K. Weber, S. Koschnick, T. Mattfeld, W. Deppert, H. Kern, G. Adler, R.M. Schmid. A tumor progression model for pancreatic cancer recapitulating the genetic alterations of the human disease. Genes Dev 15:286-93 (2001)
  13. W. Antonin, M. Wagner, D. Riedel, N. Brose, R. Jahn. Loss of the zymogen granule protein syncollin affects pancreatic protein synthesis and transport but not secretion. Mol Cell Biol 22: 1545-54 (2002)
  14. U. Seitz, M. Wagner, B. Neumaier, E. Wawra, G. Glatting, G. Leder, R.M. Schmid, S.N. Reske. Evaluation of pyrimidine metabolising enzymes and in vitro uptake of3'-[18F]fluoro-3'-deoxythymidine ([18F]FLT) in pancreatic cancer cell lines. Eur J Nucl Med Mol Imaging 29: 1174-81 (2002)
  15. F.R. Greten, C.K. Weber, T.F. Greten, G. Schneider, M. Wagner, G. Adler, R.M. Schmid. Stat3 and NF-kappaB activation prevents apoptosis in pancreatic carcinogenesis. Gastroenterology  123:2052-63 (2002)
  16. M. Wagner, C.K. Weber, F. Bressau, F.R. Greten, V. Stagge, M. Ebert, S.D. Leach, G. Adler, R.M. Schmid. Transgenic overexpression of amphiregulin induces a mitogenic response selectively in pancreatic duct cells. Gastroenterology 122: 1898-912 (2002)
  17. P. Blyszczuk, J. Czyz, G. Kania, M. Wagner, U. Roll, L. St-Onge, A.M. Wobus. Expression of Pax4 in embryonic stem cells promotes differentiation of nestin-positive progenitor and insulin-producing cells. Proc Natl Acad Sci 100: 998-1003 (2003)
  18. M. Wagner, U. Seitz, B. Neumaier, S. Schultheiß, M. Bangerter, M. Bommer, F. Leithäuser, E. Wawra, G. Munzert, S.N. Reske. 3´-[18F]Fluoro-3´-deoxythymidine ([18F]-FLT) as PET tracer for imaging proliferation in a murine B-cell lymphoma model and in the human disease. Cancer Res 63: 2681-2687 (2003)
  19. S. Liptay, C.K. Weber, L. Ludwig, M. Wagner, G. Adler, R.M. Schmid. Mitogenic and antiapoptotic role of constitutive NF-kappaB/Rel activity in pancreatic cancer. Int J Cancer 105:735-46 (2003)
  20. M. Wagner, S. Kunsch, D. Dürschmied, M. Beil, G. Adler, F. Müller, T.M. Gress. Transgenic overexpression of the oncofetal RNA binding protein KOC leads to remodelling of the exocrine pancreas. Gastroenterology: 124, 1901-14 (2003)
  21. M. Buchholz, A. Biebl, A. Neeße, M. Wagner, T. Iwamura, G. Leder, G. Adler, T.M. Gress. SERPINE2 (Protease Nexin I) Promotes Extracellular Matrix Production and Local Invasion of Pancreatic Tumors In Vivo. Cancer Res 63:4945-4951 (2003)
  22. I. Girkontaite, V. Sakk, M. Wagner, T. Borggrefe, K. Tedford, J. Chun, and K.-D. Fischer. The Sphingosine-1-Phosphate (S1P) Lysophospholipid Receptor S1P3 Regulates MAdCAM-1+ Endothelial Cells in Splenic Marginal Sinus Organization. J. Exp. Med. 200: 1491 – 1501 (2004).
  23. Michl P, Ramjaun AR, Pardo OE, Warne PH, Wagner M, Poulsom R, D'Arrigo C, Ryder K, Menke A, Gress T, Downward J.. CUTL1 is a target of TGF(beta) signaling that enhances cancer cell motility and invasiveness. Cancer Cell. 7:521-32 (2005)
  24. Tamara Aleksic, Bernd Baumann, Martin Wagner, Guido Adler, Thomas Wirth, and Christoph K Weber. Cellular immune Reaction in the Pancreas is induced by constitutively active  IKK2. Gut  56:227-36 (2007)
  25. Jungert K, Buck A, Buchholz M, Wagner M, Adler G, Gress TM, Ellenrieder V.. Smad-Sp1 complexes mediate TGF{beta}-induced early transcription of oncogenic Smad7 in pancreatic cancer cells. Carcinogenesis 27:2392-401 (2006)
  26. Buchholz M, Schatz A, Wagner M, Michl P, Linhart T, Adler G, Gress TM, Ellenrieder V.. Overexpression of c-myc in pancreatic cancer caused by ectopic activation of NFATc1 and the Ca(2+)/calcineurin signaling pathway. EMBO J. 25:3714-24 (2006)
  27. Buck A, Buchholz M, Wagner M, Adler G, Gress T, Ellenrieder V. The Tumor Suppressor KLF11 Mediates a Novel Mechanism in Transforming Growth Factor {beta}-Induced Growth Inhibition That Is Inactivated in Pancreatic Cancer. Mol Cancer Res. 4:861-872 (2006)
  28. Mario Corvero,  Claudia Fuoco, Francesco Cecconi, Martin Wagner. Analysis of apoptosome dysregulation in pancreatic cancer and of its role in chemoresistance. CanBiolTher,  angenommen 24.11.2006, in press. (geteilte Letztautorschaft F.C. und M.W.)
  29. Hanna Algül, Martin Wagner, Roland M. Schmid. Overexpression of ErbB2 in the exocrine pancreas induces an inflammatory response but no increased proliferation. Int J Cancer. 2007 Jun 1; in press
  30. Wagner M*, Baumann B*,  Aleksic T, vWichert G., Weber CK, Adler G and  Wirth T. Constitutive IKK2 activation in acinar cells is sufficient to induce pancreatitis in vivo. J Clin Invest. 117:1502-13. (2007)  (geteilte Erstautorschaft M.W. und B.B.)
  31. Ripka S, Konig A, Buchholz M, Wagner M, Sipos B, Kloppel G, Downward J, Gress T, Michl P. WNT5A--target of CUTL1 and potent modulator of tumor cell migration and invasion in pancreatic cancer. Carcinogenesis 28:1178-87. (2007)
  32. Neesse A, Wagner M, Ellenrieder V, Bachem M, Gress TM, Buchholz M. Pancreatic stellate cells potentiate proinvasive effects of SERPINE2 expression in pancreatic cancer xenograft tumors.
    Pancreatology 7:380-5. (2007)
  33. Wagner M, Koschnick S, Beilke S, Frey M, Adler G, Schmid RM.
    Selective expansion of the beta-cell compartment in the pancreas of keratinocyte growth factor transgenic mice. Am J Physiol Gastrointest Liver Physiol. 294(5):G1139-47. (2008)
  34. Juchems MS, Niess JH, Leder G, Barth TF, Adler G, Brambs HJ, Wagner M.
    Strongyloides stercoralis: a rare cause of obstructive duodenal stenosis. Digestion 77:141-4. (2008)
  35. von Figura G, Stephani J, Wagner M, Wegener M, Wolf C, Adler G, Kulaksiz H. Secondary sclerosing cholangitis after chemotherapy with bevacizumab and paclitaxel. Endoscopy 41 Suppl 2:E153-4 (2009)
  36. Beilke S, Oswald F, Genze F, Wirth T, Adler G, Wagner M. The zinc-finger protein KCMF1 is overexpressed during pancreatic cancer development and downregulation of KCMF1 inhibits pancreatic cancer development in mice. Oncogene 2010
  37. Zizer E, Beilke S, Bäuerle T, Schilling K, Möhnle U, Adler G, Fischer KD, Wagner M. Loss of lsc/p115-protein leads to neuronal hypoplasia in the esophagus and an achalasia-like phenotype in mice. Gastroenterology. 2010 Jun 20.

Übersichtsarbeiten

  1. T.M. Gress, A. Menke, M. Bachem, F. Müller-Pillasch, V. Ellenrieder, H. Weidenbach, M. Wagner, G. Adler. Role of extracellular matrix in pancreatic diseases. Digestion 59:625-37 (1998)

  2. F.R. Greten, M. Wagner, C.K. Weber, U. Zechner, G. Adler, R.M. Schmid. TGF alpha transgenic mice. A model of pancreatic cancer development. Pancreatology 1: 363-368 (2001)

  3. M. Wagner und G. Adler. Somatische Stammzellen des Pankreas. Bundesgesundheitsblatt 45: 102-107 (2004)

  4. M. Wagner, G. Adler, T. Seufferlein. Kolorektale Karzinome: Neue Entwicklungen in der Tumorprävention und in der Diagnostik der Tumorausbreitung. Chir.Gastroenterol. 21 (2005)

  5. L. St-Onge und M. Wagner. Regulation der Entwicklung des Pankreas. In D. Ganten, K. Ruckpaul (ed.) 'Molekularmedizinische Grundlagen von para- und autokrinen Regulationsstörungen', (pp25-57), Springerverlag Berlin (2006)

  6. M. Wagner. Ersetzt die CT-Kolonographie die diagnostische Koloskopie? Gastro up to date (2008)

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