Leitung

1979-1984

Resident, Board Neurology and Psychiatry (Department of  Neurology and Psychiatry, University of Münster FRG)(Prof. G. Brune, Prof. R. Tölle)

1984-1985

Stipend, Deutsche Forschungsgemeinschaft: Institute of Neurotoxicology, Albert Einstein College of Medicine, Bronx, New York (Prof. P.S. Spencer, Prof. H.H. Schaumburg)

1985-1989

Staff, Department of Neurology, University of Münster (Prof. G. Brune)

1987

Habilitation, Faculty of Medicine, University of Münster, C2 Professor of Neurology

1990-1992

Staff Scientist, Visiting Assoc. Prof., Center for Research on Occuputational and Environmental Toxicology, Portland (Oregon)

1992

Staff, Department of Epileptology, University of Bonn (Prof. C.E. Elger)

1993-1996

C3 Professor of Neurology, Vice Chairman, Department of Neurology, Humboldt University Berlin (Prof. K.-M. Einhäupl)

1996

C4 Professor of Neurology, Chair, Department of Neurology, University of Ulm

2003 -

Chair (elected) Academic Neuroscience Center, University of Ulm

2005-2009

Deputy Chair and Chair (elected), European ALS-MND-Group

2008-

Chair Scientific Council of Deutschen Stiftung Querschnittlähmung

2008-

Chair Scientific Council Deutsche Gesellschaft für Muskelkranke

2009-

Deputy Chair Word Federation of Neurology ALS Research Group

1996-

Investigator in more than 40 clinical trials

1997-   

Principal Investigator – Riluzole in Parkinson’s Disease

1998-   

Principal Investigator/Steering Committee – Vitamine E in ALS

1999-2006

Principal Investigator/Steering Committee –Riluzole in Huntington’s Disease (European Huntington´s Disease – EHDI)

2000-

Principal Investigator/Steering Committee NNIPPS Study (Natural History and Neuroprotection in Parkinson Plus Syndromes)

2001-2003

Safety Board Novartis – TCH 346

2002-2005

Steering Committee – Pentoxyphyllin in ALS (Exonhit)

2002-   

Chair, Steering Committee – ONO 2506 in ALS (ONO Pharma)

2002-2004

Advisory Board Novartis – Clinical Study of TCH 346

2005-

Principal Investigator, Steering Committee, Pioglitazone in ALS

2006-

Chair, Steering Committee – SIRONA (ONO-Pharma)

2008-

Principal Investigator Talampanel in ALS, Steering Committee

2009

          Advisory Board Hoffmann La-Roche, Drug Development in ALS

2009

          Advisory Board Knopp Pharma, Drug Development in ALS