Dr. Kathleen Schuck

Feldmann, K., C. Maurer, K. Peschke, S. Teller, K. Schuck, K. Steiger, T. Engleitner, R. Ollinger, A. Nomura, N. Wirges, A. Papargyriou, R.S. Jahan Sarker, R.A. Ranjan, Z. Dantes, W. Weichert, A.K. Rustgi, R.M. Schmid, R. Rad, G. Schneider, D. Saur, and M. Reichert, Mesenchymal Plasticity Regulated by Prrx1 Drives Aggressive Pancreatic Cancer Biology. Gastroenterology, 2021. 160(1): p. 346-361 e24.epub

Yu, Y., K. Schuck, H. Friess, and B. Kong, Targeting Aggressive Fibroblasts to Enhance the Treatment of Pancreatic Cancer. Expert Opin Ther Targets, 2021. 25(1): p. 5-13. epub.

Zhang, Z., H. Li, Y. Deng, K. Schuck, S. Raulefs, N. Maeritz, Y. Yu, T. Hechler, A. Pahl, V. Fernandez-Saiz, Y. Wan, G. Wang, T. Engleitner, R. Ollinger, R. Rad, M. Reichert, K.N. Diakopoulos, V. Weber, J. Li, S. Shen, X. Zou, J. Kleeff, A. Mihaljevic, C.W. Michalski, H. Algul, H. Friess, and B. Kong, AGR2-Dependent Nuclear Import of RNA Polymerase II Constitutes a Specific Target of Pancreatic Ductal Adenocarcinoma in the Context of Wild-Type p53. Gastroenterology, 2021.epub

Zhao, Y., B. Schoeps, D. Yao, Z. Zhang, K. Schuck, V. Tissen, C. Jager, A.M. Schlitter, R. van der Kammen, C. Ludwig, J.G. D'Haese, S. Raulefs, N. Maeritz, S. Shen, X. Zou, A. Kruger, J. Kleeff, C.W. Michalski, H. Friess, M. Innocenti, and B. Kong, mTORC1 and mTORC2 Converge on the Arp2/3 Complex to Promote Kras(G12D)-Induced Acinar-to-Ductal Metaplasia and Early Pancreatic Carcinogenesis. Gastroenterology, 2021. 160(5): p. 1755-1770 e17. epub

Lorentzen, A., P.F. Becker, J. Kosla, M. Saini, K. Weidele, P. Ronchi, C. Klein, M.J. Wolf, F. Geist, B. Seubert, M. Ringelhan, D. Mihic-Probst, K. Esser, M. Roblek, F. Kuehne, G. Bianco, T. O'Connor, Q. Muller, K. Schuck, S. Lange, D. Hartmann, S. Spaich, O. Gross, J. Utikal, S. Haferkamp, M.R. Sprick, A. Damle-Vartak, A. Hapfelmeier, N. Huser, U. Protzer, A. Trumpp, D. Saur, N. Vartak, C.A. Klein, B. Polzer, L. Borsig, and M. Heikenwalder, Single cell polarity in liquid phase facilitates tumour metastasis. Nat Commun, 2018. 9(1): p. 887. epub

Mueller, S., T. Engleitner, R. Maresch, M. Zukowska, S. Lange, T. Kaltenbacher, B. Konukiewitz, R. Ollinger, M. Zwiebel, A. Strong, H.Y. Yen, R. Banerjee, S. Louzada, B. Fu, B. Seidler, J. Gotzfried, K. Schuck, Z. Hassan, A. Arbeiter, N. Schonhuber, S. Klein, C. Veltkamp, M. Friedrich, L. Rad, M. Barenboim, C. Ziegenhain, J. Hess, O.M. Dovey, S. Eser, S. Parekh, F. Constantino-Casas, J. de la Rosa, M.I. Sierra, M. Fraga, J. Mayerle, G. Kloppel, J. Cadinanos, P. Liu, G. Vassiliou, W. Weichert, K. Steiger, W. Enard, R.M. Schmid, F. Yang, K. Unger, G. Schneider, I. Varela, A. Bradley, D. Saur, and R. Rad, Evolutionary routes and KRAS dosage define pancreatic cancer phenotypes. Nature, 2018. 554(7690): p. 62-68. epub

Reichert, M., B. Bakir, L. Moreira, J.R. Pitarresi, K. Feldmann, L. Simon, K. Suzuki, R. Maddipati, A.D. Rhim, A.M. Schlitter, M. Kriegsmann, W. Weichert, M. Wirth, K. Schuck, G. Schneider, D. Saur, A.B. Reynolds, A.J. Klein-Szanto, B. Pehlivanoglu, B. Memis, N.V. Adsay, and A.K. Rustgi, Regulation of Epithelial Plasticity Determines Metastatic Organotropism in Pancreatic Cancer. Dev Cell, 2018. 45(6): p. 696-711 e8. epub

Schuck, K., N. Schonhuber, B. Seidler, C. Veltkamp, T.B. Feyerabend, H.R. Rodewald, R.M. Schmid, G. Schneider, and D. Saur, A dual-recombinant system for time- and host-specific targeting of pancreatic cancer (Poster presentation, EPC, Toldeo, Spain). 2015.

Schonhuber, N., B. Seidler, K. Schuck, C. Veltkamp, C. Schachtler, M. Zukowska, S. Eser, T.B. Feyerabend, M.C. Paul, P. Eser, S. Klein, A.M. Lowy, R. Banerjee, F. Yang, C.L. Lee, E.J. Moding, D.G. Kirsch, A. Scheideler, D.R. Alessi, I. Varela, A. Bradley, A. Kind, A.E. Schnieke, H.R. Rodewald, R. Rad, R.M. Schmid, G. Schneider, and D. Saur, A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer. Nat Med, 2014. 20(11): p. 1340-1347. epub

Eser, S., N. Reiff, M. Messer, B. Seidler, K. Gottschalk, M. Dobler, M. Hieber, A. Arbeiter, S. Klein, B. Kong, C.W. Michalski, A.M. Schlitter, I. Esposito, A.J. Kind, L. Rad, A.E. Schnieke, M. Baccarini, D.R. Alessi, R. Rad, R.M. Schmid, G. Schneider, and D. Saur, Selective requirement of PI3K/PDK1 signaling for Kras oncogene-driven pancreatic cell plasticity and cancer. Cancer Cell, 2013. 23(3): p. 406-20. epub

Grunert, M., K. Gottschalk, J. Kapahnke, S. Gundisch, A. Kieser, and I. Jeremias, The adaptor protein FADD and the initiator caspase-8 mediate activation of NF-kappaB by TRAIL. Cell Death Dis, 2012. 3: p. e414. epub

Sievers, C., G. Billig, K. Gottschalk, and T. Rudel, Prohibitins are required for cancer cell proliferation and adhesion. PLoS One, 2010. 5(9): p. e12735. epub

Kepp, O., K. Gottschalk, Y. Churin, K. Rajalingam, V. Brinkmann, N. Machuy, G. Kroemer, and T. Rudel, Bim and Bmf synergize to induce apoptosis in Neisseria gonorrhoeae infection. PLoS Pathog, 2009. 5(3): p. e1000348. epub

Rajalingam, K., M. Oswald, K. Gottschalk, and T. Rudel, Smac/DIABLO is required for effector caspase activation during apoptosis in human cells. Apoptosis, 2007. 12(8): p. 1503-10. epub