Prof Dr med Friederike Liesche-Starnecker

Medical Director

Secretariat

Phone 08221 962163

Focal points
  • Digital and AI-supported neuropathology
  • Neuropathology of rare inflammatory and infectious encephalitis (including bornavirus encephalitis)
  • Translational neurooncology with a focus on tumour heterogeneity and microenvironment
Qualifications and prices
  • 2020: Acquisition of the "Certificate in Medical Didactics of the Bavarian Universities", basic level
  • 2019: Teaching awards: 2nd place "Lecturer of the Year 2019" in the categories "Lecture" and "Seminar" of the Faculty of Medicine (TUM)
  • 2019: Poster prize: 1st prize d. Conference of the DGNN for "The neuropathology of human bornavirus encephalitis"
  • 2018: Teaching Award: 2nd place "Lecturer of the Year 2019", category "Lecture" of the Faculty of Medicine (TUM)
  • 2017: Teaching awards: Student Teaching Award for outstanding teaching and Young Talent Award for outstanding commitment to teaching from the Faculty of Medicine (TUM)

Since 2026 Medical Director of the Institute of Neuropathology at Ulm University Hospital (UKU) and W3 Professor

2024 to 2025 Head of the Neuropathology Section at the University Hospital Augsburg (UKA)

2023 to 2024 Specialist in neuropathology at the UKA and establishment of the Neuropathology Section

2023 Completion of specialist training in the field of neuropathology

2020 Completion of habilitation in neuropathology at the Technical University of Munich (TUM): "The morphology of human bornavirus encephalitis"

2016 to 2023 Further training as a specialist in neuropathology at TUM (until 03/2022) and the UKA (04/2022-08/2023)

2017 Acquisition of the doctoral degree at the LMU; "Glycosyltransferases as markers of early tumourigenesis - immunohistochemical staining of breast carcinoma specimens"

2016 Acquisition of the medical licence to practise medicine

2009 to 2016 Medical studies at the Ludwig-Maximilians-University (LMU) and TUM

Member - German Society for Neuropathology and Neuroanatomy (DGNN)

Member - German Cancer Society (DKG)

Member - Neurooncological Working Group (NOA)

Member - German University Association (DHV)

Liesche-Starnecker F, Mielewczyk Z, Grochowski P, Jungbäck N, Adam P, Märkl B, Schlegel J. Hirnsektion in der Allgemeinpathologie. Pathologie (2026).doi: 10.1007/s00292-026-01543-0.

Reitsam NG, Gäble A, Siebenhüter L, Schaller T, Liesche-Starnecker F, Sipos E, Dintner S, Walz C, Babic J, Trepel M, Kircher M, Fincke VE, Johann PD, Märkl B, Lapa C, Enke JS. FAP expression as a marker of malignant transformation enabling in vivo characterization in peripheral nerve sheath tumors: a multimodal and translational study. Acta Neuropathol 151, 11 (2026). doi: 10.1007/s00401-026-02979-7. PMID: 41591566. PMCID: PMC12847211.

Here you will find a selection of publications before 2026. All publications can be found at PubMed and under the ORCID 0000-0003-1948-1580.

Shiban E, Krauss P, Schaller T, Konietzko I, Mögele T, Jungbäck N, Mielke D, Märkl B, Kahl KH, Mielewczyk Z, Liesche-Starnecker F. A prospective observational study of inflammatory mediators in cerebrospinal fluid after intraoperative radiotherapy of brain tumors. Ther Adv Med Oncol. 17 (2025). doi: 10.1177/17588359251389740. PMID: 41262211. PMCID: PMC12623645.

Bücheler V, Hieber D, Karthan M, Jungbäck N, Dinser M, Pohl C, Pryss R, Liesche-Starnecker F, Schobel J. Eye-Tracking in Digital Pathology: A Vendor-Agnostic Platform for Standardized and Reproducible Eye-Tracking Studies, IEEE 38th International Symposium on Computer-Based Medical Systems (CBMS) (2025), doi: 10.1109/CBMS65348.2025.00190.

Vollmuth Y, Jungbäck N, Grochowski P, Mögele T, Stark L, Zarrabi NS, Schlegel J, Schaller T, Märkl B, Matiasek K, Liesche-Starnecker F. Mapping Bornavirus encephalitis-A comparative study of viral spread and immune response in human and animal dead-end hosts. PLoS Pathog 21, 8 (2025). doi: 10.1371/journal.ppat.1013400. PMID: 40758738. PMCID: PMC12338802.

Jungbäck N, Vollmuth Y, Mögele T, Grochowski P, Schlegel J, Schaller T, Märkl B, Herden C, Matiasek K, Tappe D, Liesche-Starnecker F. Neuropathology, pathomechanism, and transmission in zoonotic Borna disease virus 1 infection: a systematic review. Lancet Infect Dis. 25, 4 (2025). doi: 10.1016/S1473-3099(24)00675-3. PMID: 39793593.

Wagner A, Brielmaier MC, Kampf C, Baumgart L, Aftahy AK, Meyer HS, Kehl V, Höhne J, Schebesch KM, Schmidt NO, Zoubaa S, Riemenschneider MJ, Ratliff M, Enders F, von Deimling A, Liesche-Starnecker F, Delbridge C, Schlegel J, Meyer B, Gempt J. Fluorescein-stained confocal laser endomicroscopy versus conventional frozen section for intraoperative histopathological assessment of intracranial tumors. Neuro Oncol. 26, 5 (2024). doi: 10.1093/neuonc/noae006. PMID: 38243410. PMCID: PMC11066924.

Godbole S, Voß H, Gocke A, Schlumbohm S, Schumann Y, Peng B, Mynarek M, Rutkowski S, Dottermusch M, Dorostkar MM, Korshunov A, Mair T, Pfister SM, Kwiatkowski M, Hotze M, Neumann P, Hartmann C, Weis J, Liesche-Starnecker F, Guan Y, Moritz M, Siebels B, Struve N, Schlüter H, Schüller U, Krisp C, Neumann JE. Multiomic profiling of medulloblastoma reveals subtype-specific targetable alterations at the proteome and N-glycan level. Nat Commun. 15, 6237 (2024). doi: 10.1038/s41467-024-50554-z. PMID: 39043693. PMCID: PMC11266559.

Ebinger A, Santos PD, Pfaff F, Dürrwald R, Kolodziejek J, Schlottau K, Ruf V, Liesche-Starnecker F, Ensser A, Korn K, Ulrich R, Fürstenau J, Matiasek K, Hansmann F, Seuberlich T, Nobach D, Müller M, Neubauer-Juric A, Suchowski M, Bauswein M, Niller HH, Schmidt B, Tappe D, Cadar D, Homeier-Bachmann T, Haring VC, Pörtner K, Frank C, Mundhenk L, Hoffmann B, Herms J, Baumgärtner W, Nowotny N, Schlegel J, Ulrich RG, Beer M, Rubbenstroth D. Lethal Borna disease virus 1 infections of humans and animals - in-depth molecular epidemiology and phylogeography. Nat Commun. 15, 7908 (2024). doi: 10.1038/s41467-024-52192-x. PMID: 39256401. PMCID: PMC11387626.

Bayas A, Menacher M, Lapa C, Tappe D, Maurer C, Liesche-Starnecker F, Schneider H, Naumann M. 18fluorodeoxyglucose PET/CT as possible early diagnostic tool preceding MRI changes in Borna disease virus 1 encephalitis. Lancet. 403, 10427 (2024). doi: 10.1016/S0140-6736(24)00049-7. PMID: 38368015.

Hieber D, Haisch N, Grambow G, Holl F, Liesche-Starnecker F, Pryss R, Schlegel J, Schobel J. Comparing nnU-Net and deepflash2 for Histopathological Tumor Segmentation. Stud Health Technol Inform. 316 (2024). doi: 10.3233/SHTI240487. PMID: 39176815.

Vollmuth Y, Jungbäck N, Mögele T, Schmidt-Graf F, Wunderlich S, Schimmel M, Rothe C, Stark L, Schlegel J, Rieder G, Richter T, Schaller T, Tappe D, Märkl B, Matiasek K, Liesche-Starnecker F. Comparative study of virus and lymphocyte distribution with clinical data suggests early high dose immunosuppression as potential key factor for the therapy of patients with BoDV-1 infection. Emerg Microbes & Infections 13 (2024). doi: 10.1080/22221751.2024.2350168; PMID: 38687703. PMCID: PMC11107860.

Prokop G, Wiestler B, Hieber D, Withake F, Mayer K, Gempt J, Delbridge C, Schmidt-Graf F, Pfarr N, Märkl B, Schlegel J, Liesche-Starnecker F. Multiscale quantification of morphological heterogeneity with creation of a predictor of longer survival in glioblastoma. Int J Cancer. 153, 9 (2023). doi: 10.1002/ijc.34665. PMID: 37501565.

Liesche-Starnecker F, Schifferer M, Schlegel J, Vollmuth Y, Rubbenstroth D, Delbridge C, Gempt J, Lorenzl S, Schnurbus L, Misgeld T, Rosati M, Beer M, Matiasek K, Wunderlich S, Finck T. Hemorrhagic lesion with detection of infected endothelial cells in human bornavirus encephalitis. Acta Neuropathol. 144, 2 (2022). doi: 10.1007/s00401-022-02442-3. PMID: 35657496. PMCID: PMC9164175.