Onkologische Chirurgie

Kolorektale Chirurgie

Pankreas- und Leberchirurgie

Minimal-invasive OP-Verfahren

Proktologie/chirurgische Endoskopie

Approbation (1994)

Promotion (1995)

Habilitation und Erteilung der Lehrbefugnis für das Fach Chirurgie (2002)

Facharzt für Chirurgie (2003)

Schwerpunkt Viszeralchirurgie (2006)

apl-Professor (2006)

Zusatzweiterbildung: Spezielle Viszeralchirurgie (2011)

Seit 01.01.2009 Leitender Oberarzt der Klinik

Seit 01.10.2020 Stellvertretender Ärztlicher Direktor der Klinik 

Steinkraus KC, Jötten L, Traub B, Zaimi M, Denzinger M, Michalski CW, Kornmann M, Hüttner FJ. Robotic Liver Surgery for Alveolar Echinococcosis: A Single-Centre Experience. Pathogens. 2022 Oct 31;11(11):1276. doi: 10.3390/pathogens11111276. PMID: 36365027; PMCID: PMC9698832.
 

Shi J, Yang X, Kang Q, Lu J, Denzinger M, Kornmann M, Traub B. JNK inhibitor IX restrains pancreatic cancer through p53 and p21. Front Oncol. 2022 Dec 7;12:1006131. doi: 10.3389/fonc.2022.1006131. PMID: 36568248; PMCID: PMC9768178.
 

Shi J, Shen X, Kang Q, Yang X, Denzinger M, Kornmann M, Traub B. Loss of Interleukin-13-Receptor-Alpha-1 Induces Apoptosis and Promotes EMT in Pancreatic Cancer. Int J Mol Sci. 2022 Mar 26;23(7):3659. doi: 10.3390/ijms23073659. PMID: 35409019; PMCID: PMC8998778.
 

Kornmann M, Kleger A. Editorial: Multimodality Treatment in Pancreatic Ductal Adenocarcinoma - Current Options and the Future Impact of Molecular Biological Profiling. Visc Med. 2022 Feb;38(1):1-3. doi: 10.1159/000521419. Epub 2022 Jan 24. PMID: 35291696; PMCID: PMC8874236.
 

Scheele J, Lemke J, Wittau M, Sander S, Henne-Bruns D, Kornmann M. Quality of Life after Rectal Cancer Resection Comparing Anterior Resection, Abdominoperineal Resection, and Complicated Cases. Visc Med. 2022 Apr;38(2):138-149. doi: 10.1159/000520945. Epub 2022 Jan 17. PMID: 35614891; PMCID: PMC9082171.
 

Tian X, Traub B, Shi J, Huber N, Schreiner S, Chen G, Zhou S, Henne-Bruns D, Knippschild U, Kornmann M. c-Jun N-terminal kinase 2 suppresses pancreatic cancer growth and invasion and is opposed by c-Jun N-terminal kinase 1. Cancer Gene Ther. 2022 Jan;29(1):73-86. doi: 10.1038/s41417-020-00290-5. Epub 2021 Feb 1. PMID: 33526844; PMCID: PMC8761571.
 

Jötten L, Steinkraus KC, Traub B, Graf S, Mihaljevic AL, Kornmann M, Michalski CW, Hüttner FJ. Impact of perioperative steroid administration in patients undergoing elective liver resection: meta-analysis. BJS Open. 2022 Nov 2;6(6): zrac139. doi: 10.1093/bjsopen/zrac139. PMID: 36537738; PMCID: PMC9764439.

Kleger A, Ellenrieder V, Friess H, Michl P, Schneider M, Yang Y, Kornmann M. Discussion: Current Multimodality Treatment Options in Pancreatic Cancer in Clinical Practice - What Is the Future Impact of Molecular Biological Profiling? Visc Med. 2022 Feb;38(1):49-55. doi: 10.1159/000521847. Epub 2022 Jan 21. PMID: 35295897; PMCID: PMC8874242.

Seufferlein T, Uhl W, Kornmann M, Algül H, Friess H, König A, Ghadimi M, Gallmeier E, Bartsch DK, Lutz MP, Metzger R, Wille K, Gerdes B, Schimanski CC, Graupe F, Kunzmann V, Klein I, Geissler M, Staib L, Waldschmidt D, Bruns C, Wittel U, Fichtner-Feigl S, Daum S, Hinke A, Blome L, Tannapfel A, Kleger A, Berger AW, Kestler AMR, Schuhbaur JS, Perkhofer L, Tempero M, Reinacher-Schick AC, Ettrich TJ. Perioperative or only adjuvant gemcitabine plus nab-paclitaxel for resectable pancreatic cancer (NEONAX)-a randomized phase II trial of the AIO pancreatic cancer group. Ann Oncol. 2023 Jan;34(1):91-100. doi: 10.1016/j.annonc.2022.09.161. Epub 2022 Oct 7. PMID: 36209981.

Beutel A K, Schutte L, Scheible J, Roger E, Muller M, Perkhofer L, Kestler A, Kraus J M, Kestler H A, Barth T F E, Lemke J, Kornmann M, Ettrich T J, Gout J, Seufferlein T, Kleger A. 2021. A Prospective Feasibility Trial to Challenge Patient-Derived Pancreatic Cancer Organoids in Predicting Treatment Response. Cancers (Basel)  13(11) https://www.ncbi.nlm.nih.gov/pubmed/34064221. 10.3390/cancers13112539

Brand M, Reimer S, Reibetanz J, Flemming S, Kornmann M, Meining A. 2021. Endoscopic full thickness resection vs. transanal endoscopic microsurgery for local treatment of rectal neuroendocrine tumors - a retrospective analysis. Int J Colorectal Dis  36(5): p. 971-976 https://www.ncbi.nlm.nih.gov/pubmed/33215239. 10.1007/s00384-020-03800-x

Chen K, Wang Q, Kornmann M, Tian X, Yang Y. 2021. The Role of Exosomes in Pancreatic Cancer From Bench to Clinical Application: An Updated Review. Front Oncol  11: p. 644358 https://www.ncbi.nlm.nih.gov/pubmed/33718244. 10.3389/fonc.2021.644358

Kliesch S, Schmidt S, Wilborn D, Aigner C, Albrecht W, Bedke J, Beintker M, Beyersdorff D, Bokemeyer C, Busch J, Classen J, de Wit M, Dieckmann K P, Diemer T, Dieing A, Gockel M, Gockel-Beining B, Hakenberg O W, Heidenreich A, Heinzelbecker J, Herkommer K, Hermanns T, Kaufmann S, Kornmann M, Kotzerke J, Krege S, Kristiansen G, Lorch A, Muller A C, Oechsle K, Ohloff T, Oing C, Otto U, Pfister D, Pichler R, Recken H, Rick O, Rudolph Y, Ruf C, Schirren J, Schmelz H, Schmidberger H, Schrader M, Schweyer S, Seeling S, Souchon R, Winter C, Wittekind C, Zengerling F, Zermann D H, Zillmann R, Albers P. 2021. Management of Germ Cell Tumours of the Testis in Adult Patients. German Clinical Practice Guideline Part I: Epidemiology, Classification, Diagnosis, Prognosis, Fertility Preservation, and Treatment Recommendations for Localized Stages. Urol Int  105(3-4): p. 169-180 https://www.ncbi.nlm.nih.gov/pubmed/33412555. 10.1159/000510407

Kliesch S, Schmidt S, Wilborn D, Aigner C, Albrecht W, Bedke J, Beintker M, Beyersdorff D, Bokemeyer C, Busch J, Classen J, de Wit M, Dieckmann K P, Diemer T, Dieing A, Gockel M, Gockel-Beining B, Hakenberg O W, Heidenreich A, Heinzelbecker J, Herkommer K, Hermanns T, Kaufmann S, Kornmann M, Kotzerke J, Krege S, Kristiansen G, Lorch A, Muller A C, Oechsle K, Ohloff T, Oing C, Otto U, Pfister D, Pichler R, Recken H, Rick O, Rudolph Y, Ruf C, Schirren J, Schmelz H, Schmidberger H, Schrader M, Schweyer S, Seeling S, Souchon R, Winter C, Wittekind C, Zengerling F, Zermann D H, Zillmann R, Albers P. 2021. Management of Germ Cell Tumours of the Testes in Adult Patients: German Clinical Practice Guideline, PART II - Recommendations for the Treatment of Advanced, Recurrent, and Refractory Disease and Extragonadal and Sex Cord/Stromal Tumours and for the Management of Follow-Up, Toxicity, Quality of Life, Palliative Care, and Supportive Therapy. Urol Int  105(3-4): p. 181-191 https://www.ncbi.nlm.nih.gov/pubmed/33486494. 10.1159/000511245

Lakemeyer L, Sander S, Wittau M, Henne-Bruns D, Kornmann M, Lemke J. 2021. Diagnostic and Prognostic Value of CEA and CA19-9 in Colorectal Cancer. Diseases  9(1) https://www.ncbi.nlm.nih.gov/pubmed/33802962. 10.3390/diseases9010021

Shi J, Song X, Traub B, Luxenhofer M, Kornmann M. 2021. Involvement of IL-4, IL-13 and Their Receptors in Pancreatic Cancer. Int J Mol Sci  22(6) https://www.ncbi.nlm.nih.gov/pubmed/33804263. 10.3390/ijms22062998

Song X, Traub B, Shi J, Kornmann M. 2021. Possible Roles of Interleukin-4 and -13 and Their Receptors in Gastric and Colon Cancer. Int J Mol Sci  22(2) https://www.ncbi.nlm.nih.gov/pubmed/33450900. 10.3390/ijms22020727

Steinacker J P, Steinacker-Stanescu N, Ettrich T, Kornmann M, Kneer K, Beer A, Beer M, Schmidt S A. 2021. Computed Tomography-Based Tumor Heterogeneity Analysis Reveals Differences in a Cohort with Advanced Pancreatic Carcinoma under Palliative Chemotherapy. Visc Med  37(1): p. 77-83 https://www.ncbi.nlm.nih.gov/pubmed/33718486. 10.1159/000506656

Tian X, Traub B, Shi J, Huber N, Schreiner S, Chen G, Zhou S, Henne-Bruns D, Knippschild U, Kornmann M. 2021. c-Jun N-terminal kinase 2 suppresses pancreatic cancer growth and invasion and is opposed by c-Jun N-terminal kinase 1. Cancer Gene Ther  https://www.ncbi.nlm.nih.gov/pubmed/33526844. 10.1038/s41417-020-00290-5

Traub B, Link K H, Kornmann M. 2021. Curing pancreatic cancer. Semin Cancer Biol  https://www.ncbi.nlm.nih.gov/pubmed/34062264. 10.1016/j.semcancer.2021.05.030

Traub B, Roth A, Kornmann M, Knippschild U, Bischof J. 2021. Stress-activated kinases as therapeutic targets in pancreatic cancer. World J Gastroenterol  27(30): p. 4963-4984 https://www.ncbi.nlm.nih.gov/pubmed/34497429. 10.3748/wjg.v27.i30.4963

Tian X, Traub B, Xie X, Zhou S, Henne-Bruns D, Knippschild U, Kornmann M. 2020. Opposing Oncogenic Functions of p38 Mitogen-activated Protein Kinase Alpha and Beta in Human Pancreatic Cancer Cells. Anticancer Res  40(10): p. 5545-5556 https://www.ncbi.nlm.nih.gov/pubmed/32988878. 10.21873/anticanres.14567

Yokoyama S, Hamada T, Higashi M, Matsuo K, Maemura K, Kurahara H, Horinouchi M, Hiraki T, Sugimoto T, Akahane T, Yonezawa S, Kornmann M, Batra S K, Hollingsworth M A, Tanimoto A. 2020. Predicted Prognosis of Patients with Pancreatic Cancer by Machine Learning. Clin Cancer Res  26(10): p. 2411-2421 https://www.ncbi.nlm.nih.gov/pubmed/31992588. 10.1158/1078-0432.CCR-19-1247

Berger A W, Schwerdel D, Reinacher-Schick A, Uhl W, Algul H, Friess H, Janssen K P, Konig A, Ghadimi M, Gallmeier E, Bartsch D K, Geissler M, Staib L, Tannapfel A, Kleger A, Beutel A, Schulte L A, Kornmann M, Ettrich T J, Seufferlein T. 2019. A Blood-Based Multi Marker Assay Supports the Differential Diagnosis of Early-Stage Pancreatic Cancer. Theranostics  9(5): p. 1280-1287 https://www.ncbi.nlm.nih.gov/pubmed/30867830. 10.7150/thno.29247

Liu C, Witt L, Ianes C, Bischof J, Bammert M T, Baier J, Kirschner S, Henne-Bruns D, Xu P, Kornmann M, Peifer C, Knippschild U. 2019. Newly Developed CK1-Specific Inhibitors Show Specifically Stronger Effects on CK1 Mutants and Colon Cancer Cell Lines. Int J Mol Sci  20(24) https://www.ncbi.nlm.nih.gov/pubmed/31817920. 10.3390/ijms20246184

Paschke S, Hebart H, Goeb R, Staib L, Fleck U, Henne-Bruns D, Sander S, Link K H, Kornmann M. 2019. Adjuvant Chemotherapy of Locally Advanced Colon Cancer: Final Results of a Randomized Trial Comparing 5-Fluorouracil and Folinic Acid with Folfiri. Visc Med  35(2): p. 124-132 https://www.ncbi.nlm.nih.gov/pubmed/31192246. 10.1159/000491648

Zhang Z, Li J, Guo H, Wang F, Ma L, Du C, Wang Y, Wang Q, Kornmann M, Tian X, Yang Y. 2019. BRM transcriptionally regulates miR-302a-3p to target SOCS5/STAT3 signaling axis to potentiate pancreatic cancer metastasis. Cancer Lett  449: p. 215-225 https://www.ncbi.nlm.nih.gov/pubmed/30790683. 10.1016/j.canlet.2019.02.031

Ettrich T J, Berger A W, Perkhofer L, Daum S, Konig A, Dickhut A, Wittel U, Wille K, Geissler M, Algul H, Gallmeier E, Atzpodien J, Kornmann M, Muche R, Prasnikar N, Tannapfel A, Reinacher-Schick A, Uhl W, Seufferlein T. 2018. Neoadjuvant plus adjuvant or only adjuvant nab-paclitaxel plus gemcitabine for resectable pancreatic cancer - the NEONAX trial (AIO-PAK-0313), a prospective, randomized, controlled, phase II study of the AIO pancreatic cancer group. BMC Cancer  18(1): p. 1298 https://www.ncbi.nlm.nih.gov/pubmed/30594153. 10.1186/s12885-018-5183-y

Ma L, Tian X, Guo H, Zhang Z, Du C, Wang F, Xie X, Gao H, Zhuang Y, Kornmann M, Gao H, Yang Y. 2018. Long noncoding RNA H19 derived miR-675 regulates cell proliferation by down-regulating E2F-1 in human pancreatic ductal adenocarcinoma. J Cancer  9(2): p. 389-399 https://www.ncbi.nlm.nih.gov/pubmed/29344285. 10.7150/jca.21347

Ma L, Wang F, Du C, Zhang Z, Guo H, Xie X, Gao H, Zhuang Y, Kornmann M, Gao H, Tian X, Yang Y. 2018. Long non-coding RNA MEG3 functions as a tumour suppressor and has prognostic predictive value in human pancreatic cancer. Oncol Rep  39(3): p. 1132-1140 https://www.ncbi.nlm.nih.gov/pubmed/29328401. 10.3892/or.2018.6178

Manzini G, Ettrich T J, Kremer M, Kornmann M, Henne-Bruns D, Eikema D A, Schlattmann P, de Wreede L C. 2018. Advantages of a multi-state approach in surgical research: how intermediate events and risk factor profile affect the prognosis of a patient with locally advanced rectal cancer. BMC Med Res Methodol  18(1): p. 23 https://www.ncbi.nlm.nih.gov/pubmed/29439652. 10.1186/s12874-018-0476-z

Paschke S, Jafarov S, Staib L, Kreuser E D, Maulbecker-Armstrong C, Roitman M, Holm T, Harris C C, Link K H, Kornmann M. 2018. Are Colon and Rectal Cancer Two Different Tumor Entities? A Proposal to Abandon the Term Colorectal Cancer. Int J Mol Sci  19(9) https://www.ncbi.nlm.nih.gov/pubmed/30200215. 10.3390/ijms19092577

Scheele J, Schmidt S A, Tenzer S, Henne-Bruns D, Kornmann M. 2018. Overstaging: A Challenge in Rectal Cancer Treatment. Visc Med  34(4): p. 301-306 https://www.ncbi.nlm.nih.gov/pubmed/30345289. 10.1159/000488652

Link K H, Coy P, Roitman M, Link C, Kornmann M, Staib L. 2017. Minimum Volume Discussion in the Treatment of Colon and Rectal Cancer: A Review of the Current Status and Relevance of Surgeon and Hospital Volume regarding Result Quality and the Impact on Health Economics. Visc Med  33(2): p. 140-147 https://www.ncbi.nlm.nih.gov/pubmed/28560230. 10.1159/000456044

Traub B, Sun L, Ma Y, Xu P, Lemke J, Paschke S, Henne-Bruns D, Knippschild U, Kornmann M. 2017. Endogenously Expressed IL-4Ralpha Promotes the Malignant Phenotype of Human Pancreatic Cancer In Vitro and In Vivo. Int J Mol Sci  18(4) https://www.ncbi.nlm.nih.gov/pubmed/28350325. 10.3390/ijms18040716

Wittau M, Paschke S, Kurlbaum M, Scheele J, Ly N S, Hemper E, Kornmann M, Henne-Bruns D, Bulitta J B. 2017. Population Pharmacokinetics and Target Attainment of Ertapenem in Plasma and Tissue Assessed via Microdialysis in Morbidly Obese Patients after Laparoscopic Visceral Surgery. Antimicrob Agents Chemother  61(1) https://www.ncbi.nlm.nih.gov/pubmed/27795367. 10.1128/AAC.00952-16

Zhang Z, Wang F, Du C, Guo H, Ma L, Liu X, Kornmann M, Tian X, Yang Y. 2017. BRM/SMARCA2 promotes the proliferation and chemoresistance of pancreatic cancer cells by targeting JAK2/STAT3 signaling. Cancer Lett  402: p. 213-224 https://www.ncbi.nlm.nih.gov/pubmed/28602977. 10.1016/j.canlet.2017.05.006

Hemper E, Wittau M, Lemke J, Kornmann M, Henne-Bruns D. 2016. Management of a giant perineal condylomata acuminata. GMS Interdiscip Plast Reconstr Surg DGPW  5: p. Doc07 https://www.ncbi.nlm.nih.gov/pubmed/26814336. 10.3205/iprs000086

Lemke J, Cammerer G, Ganser J, Scheele J, Xu P, Sander S, Henne-Bruns D, Kornmann M. 2016. Survival and Prognostic Factors of Colorectal Liver Metastases After Surgical and Nonsurgical Treatment. Clin Colorectal Cancer  15(4): p. e183-e192 https://www.ncbi.nlm.nih.gov/pubmed/27269232. 10.1016/j.clcc.2016.04.007

Lemke J, Schmidt S A, Kornmann M, Orend K H, Henne-Bruns D. 2016. Challenging the limits in pancreatic surgery: A case report. Int J Surg Case Rep  29: p. 151-154 https://www.ncbi.nlm.nih.gov/pubmed/27855353. 10.1016/j.ijscr.2016.10.062

Ma L, Tian X, Wang F, Zhang Z, Du C, Xie X, Kornmann M, Yang Y. 2016. The long noncoding RNA H19 promotes cell proliferation via E2F-1 in pancreatic ductal adenocarcinoma. Cancer Biol Ther  17(10): p. 1051-1061 https://www.ncbi.nlm.nih.gov/pubmed/27573434. 10.1080/15384047.2016.1219814

Schulte-Kemna L, Kornmann M, Kleger A. 2016. An Exceptional Cause of Epigastric Pain. Gastroenterology  150(7): p. e1-e2 https://www.ncbi.nlm.nih.gov/pubmed/27143590. 10.1053/j.gastro.2016.02.002

von Witzleben A, Goerttler L T, Lennerz J, Weissinger S, Kornmann M, Mayer-Steinacker R, von Baer A, Schultheiss M, Moller P, Barth T F. 2016. In chordoma, metastasis, recurrences, Ki-67 index, and a matrix-poor phenotype are associated with patients' shorter overall survival. Eur Spine J  25(12): p. 4016-4024 https://www.ncbi.nlm.nih.gov/pubmed/26399506. 10.1007/s00586-015-4242-1

Wang F, Ma L, Zhang Z, Liu X, Gao H, Zhuang Y, Yang P, Kornmann M, Tian X, Yang Y. 2016. Hedgehog Signaling Regulates Epithelial-Mesenchymal Transition in Pancreatic Cancer Stem-Like Cells. J Cancer  7(4): p. 408-17 https://www.ncbi.nlm.nih.gov/pubmed/26918054. 10.7150/jca.13305

Yokoyama S, Higashi M, Kitamoto S, Oeldorf M, Knippschild U, Kornmann M, Maemura K, Kurahara H, Wiest E, Hamada T, Kitazono I, Goto Y, Tasaki T, Hiraki T, Hatanaka K, Mataki Y, Taguchi H, Hashimoto S, Batra S K, Tanimoto A, Yonezawa S, Hollingsworth M A. 2016. Aberrant methylation of MUC1 and MUC4 promoters are potential prognostic biomarkers for pancreatic ductal adenocarcinomas. Oncotarget  7(27): p. 42553-42565 https://www.ncbi.nlm.nih.gov/pubmed/27283771. 10.18632/oncotarget.9924

Engler C C, Lemke J, Kornmann M, Barth T F, Schmidt S A, Henne-Bruns D. 2015. Ectopic spleen and liver hemangioma mimicking metastatic pancreatic neuroendocrine tumor. Int J Surg Case Rep  17: p. 139-42 https://www.ncbi.nlm.nih.gov/pubmed/26670205. 10.1016/j.ijscr.2015.10.041

Mayer B, Sander S, Paschke S, Henne-Bruns D, Link K H, Kornmann M, Study Group Oncology of Gastrointestinal T. 2015. Stratified Survival Analysis After Adjuvant Chemotherapy of Colon Cancer Reveals a Benefit for Older Patients. Anticancer Res  35(10): p. 5587-93 https://www.ncbi.nlm.nih.gov/pubmed/26408730.

Richter J, Ullah K, Xu P, Alscher V, Blatz A, Peifer C, Halekotte J, Leban J, Vitt D, Holzmann K, Bakulev V, Pinna L A, Henne-Bruns D, Hillenbrand A, Kornmann M, Leithauser F, Bischof J, Knippschild U. 2015. Effects of altered expression and activity levels of CK1delta and varepsilon on tumor growth and survival of colorectal cancer patients. Int J Cancer  136(12): p. 2799-810 https://www.ncbi.nlm.nih.gov/pubmed/25404202. 10.1002/ijc.29346

Scheele J, Lemke J, Meier M, Sander S, Henne-Bruns D, Kornmann M. 2015. Quality of Life After Sphincter-Preserving Rectal Cancer Resection. Clin Colorectal Cancer  14(4): p. e33-40 https://www.ncbi.nlm.nih.gov/pubmed/26164498. 10.1016/j.clcc.2015.05.012

von Witzleben A, Goerttler L T, Marienfeld R, Barth H, Lechel A, Mellert K, Bohm M, Kornmann M, Mayer-Steinacker R, von Baer A, Schultheiss M, Flanagan A M, Moller P, Bruderlein S, Barth T F. 2015. Preclinical Characterization of Novel Chordoma Cell Systems and Their Targeting by Pharmocological Inhibitors of the CDK4/6 Cell-Cycle Pathway. Cancer Res  75(18): p. 3823-31 https://www.ncbi.nlm.nih.gov/pubmed/26183925. 10.1158/0008-5472.CAN-14-3270

Hofmann S, Barth T F, Kornmann M, Henne-Bruns D. 2014. Appendix carcinoid associated with the Peutz-Jeghers syndrome. Int J Surg Case Rep  5(12): p. 964-7 https://www.ncbi.nlm.nih.gov/pubmed/25460448. 10.1016/j.ijscr.2014.06.024

Lemke J, Schafer D, Sander S, Henne-Bruns D, Kornmann M. 2014. Survival and prognostic factors in pancreatic and ampullary cancer. Anticancer Res  34(6): p. 3011-20 https://www.ncbi.nlm.nih.gov/pubmed/24922667.

Lemke J, Scheele J, Kapapa T, von Karstedt S, Wirtz C R, Henne-Bruns D, Kornmann M. 2014. Brain metastases in gastrointestinal cancers: is there a role for surgery? Int J Mol Sci  15(9): p. 16816-30 https://www.ncbi.nlm.nih.gov/pubmed/25247579. 10.3390/ijms150916816

Liu X, Tian X, Wang F, Ma Y, Kornmann M, Yang Y. 2014. BRG1 promotes chemoresistance of pancreatic cancer cells through crosstalking with Akt signalling. Eur J Cancer  50(13): p. 2251-62 https://www.ncbi.nlm.nih.gov/pubmed/24953335. 10.1016/j.ejca.2014.05.017

Scheele J, Lemke J, Barth T F, Juchems M, Wittau M, Kornmann M, Henne-Bruns D. 2014. Chondroid hamartoma of the liver. GMS Interdiscip Plast Reconstr Surg DGPW  3: p. Doc16 https://www.ncbi.nlm.nih.gov/pubmed/26504727. 10.3205/iprs000057

Thomaidis T, Maderer A, Formentini A, Bauer S, Trautmann M, Schwarz M, Neumann W, Kittner J M, Schad A, Link K H, Rey J W, Weinmann A, Hoffman A, Galle P R, Kornmann M, Moehler M. 2014. Proteins of the VEGFR and EGFR pathway as predictive markers for adjuvant treatment in patients with stage II/III colorectal cancer: results of the FOGT-4 trial. J Exp Clin Cancer Res  33: p. 83 https://www.ncbi.nlm.nih.gov/pubmed/25272957. 10.1186/s13046-014-0083-8

Fensterer H, Schade-Brittinger C, Muller H H, Tebbe S, Fass J, Lindig U, Settmacher U, Schmidt W E, Marten A, Ebert M P, Kornmann M, Hofheinz R, Endlicher E, Brendel C, Barth P J, Bartsch D K, Michl P, Gress T M, Arbeitsgemeinschaft Internistische O. 2013. Multicenter phase II trial to investigate safety and efficacy of gemcitabine combined with cetuximab as adjuvant therapy in pancreatic cancer (ATIP). Ann Oncol  24(10): p. 2576-2581 https://www.ncbi.nlm.nih.gov/pubmed/23897705. 10.1093/annonc/mdt270

Kornmann M, Staib L, Wiegel T, Kron M, Henne-Bruns D, Link K H, Formentini A, Study Group Oncology of Gastrointestinal T. 2013. Long-term results of 2 adjuvant trials reveal differences in chemosensitivity and the pattern of metastases between colon cancer and rectal cancer. Clin Colorectal Cancer  12(1): p. 54-61 https://www.ncbi.nlm.nih.gov/pubmed/23107590. 10.1016/j.clcc.2012.07.005

Lemke J, Scheele J, Kapapa T, Wirtz C R, Henne-Bruns D, Kornmann M. 2013. Brain metastasis in pancreatic cancer. Int J Mol Sci  14(2): p. 4163-73 https://www.ncbi.nlm.nih.gov/pubmed/23429199. 10.3390/ijms14024163

Schmid S J, Glatzel M C, Welke C, Kornmann M, Kleger A, Barth T F, Fulda S, Lennerz J K, Moller P. 2013. Absence of FLICE-inhibitory protein is a novel independent prognostic marker for very short survival in pancreatic ductal adenocarcinoma. Pancreas  42(7): p. 1114-9 https://www.ncbi.nlm.nih.gov/pubmed/24005232. 10.1097/MPA.0b013e31829655ed

Tsioplis C, Brockschmidt C, Sander S, Henne-Bruns D, Kornmann M. 2013. Factors influencing the course of acute appendicitis in adults and children. Langenbecks Arch Surg  398(6): p. 857-67 https://www.ncbi.nlm.nih.gov/pubmed/23832465. 10.1007/s00423-013-1096-z

Wang J C, Thiere M, Henne-Bruns D, Knippschild U, Kornmann M. 2013. Inhibition of pancreatic cancer cell growth in vivo using a tetracycline-inducible cyclin D1 antisense expression system. Pancreas  42(1): p. 141-8 https://www.ncbi.nlm.nih.gov/pubmed/22722256. 10.1097/MPA.0b013e3182546de5

Cammerer G, Formentini A, Karletshofer M, Henne-Bruns D, Kornmann M. 2012. Evaluation of important prognostic clinical and pathological factors in gastric cancer. Anticancer Res  32(5): p. 1839-42 https://www.ncbi.nlm.nih.gov/pubmed/22593471.

Formentini A, Braun P, Fricke H, Link K H, Henne-Bruns D, Kornmann M. 2012. Expression of interleukin-4 and interleukin-13 and their receptors in colorectal cancer. Int J Colorectal Dis  27(10): p. 1369-76 https://www.ncbi.nlm.nih.gov/pubmed/22441356. 10.1007/s00384-012-1456-0

Formentini A, Henne-Bruns D, Kornmann M. 2012. Thymidylate synthase and cyclin D1 protein expression in lymph node negative colorectal cancer: role as prognostic factors? Hepatogastroenterology  59(118): p. 1859-64 https://www.ncbi.nlm.nih.gov/pubmed/22819905. 10.5754/hge10428

Hofmann S, Kornmann M, Henne-Bruns D, Formentini A. 2012. Traumatic diaphragmatic ruptures: clinical presentation, diagnosis and surgical approach in adults. GMS Interdiscip Plast Reconstr Surg DGPW  1: p. Doc02 https://www.ncbi.nlm.nih.gov/pubmed/26504686. 10.3205/iprs000002

Hofmann S, Vetter J, Wachter C, Henne-Bruns D, Porzsolt F, Kornmann M. 2012. Visual AIDS for multimodal treatment options to support decision making of patients with colorectal cancer. BMC Med Inform Decis Mak  12: p. 118 https://www.ncbi.nlm.nih.gov/pubmed/23092310. 10.1186/1472-6947-12-118

Kornmann M, Hebart H, Danenberg K, Goeb R, Staib L, Kron M, Henne-Bruns D, Danenberg P, Link K H. 2012. Response prediction in metastasised colorectal cancer using intratumoural thymidylate synthase: results of a randomised multicentre trial. Eur J Cancer  48(10): p. 1443-51 https://www.ncbi.nlm.nih.gov/pubmed/22133572. 10.1016/j.ejca.2011.11.007

Scheele J, Barth T F, Wittau M, Juchems M, Henne-Bruns D, Kornmann M. 2012. Cystic teratoma of the pancreas. Anticancer Res  32(3): p. 1075-80 https://www.ncbi.nlm.nih.gov/pubmed/22399635.

Tian X, Chen G, Zhou S, Henne-Bruns D, Bachem M, Kornmann M. 2012. Interactions of pancreatic cancer and stellate cells are mediated by FGFR1-III isoform expression. Hepatogastroenterology  59(117): p. 1604-8 https://www.ncbi.nlm.nih.gov/pubmed/22683979. 10.5754/hge10366

Tikidzhieva A, Benner A, Michel S, Formentini A, Link K H, Dippold W, von Knebel Doeberitz M, Kornmann M, Kloor M. 2012. Microsatellite instability and Beta2-Microglobulin mutations as prognostic markers in colon cancer: results of the FOGT-4 trial. Br J Cancer  106(6): p. 1239-45 https://www.ncbi.nlm.nih.gov/pubmed/22353804. 10.1038/bjc.2012.53

Giehl K, Bachem M, Beil M, Bohm B O, Ellenrieder V, Fulda S, Gress T M, Holzmann K, Kestler H A, Kornmann M, Menke A, Moller P, Oswald F, Schmid R M, Schmidt V, Schirmbeck R, Seufferlein T, von Wichert G, Wagner M, Walther P, Wirth T, Adler G. 2011. Inflammation, regeneration, and transformation in the pancreas: results of the Collaborative Research Center 518 (SFB 518) at the University of Ulm. Pancreas  40(4): p. 489-502 https://www.ncbi.nlm.nih.gov/pubmed/21483252. 10.1097/MPA.0b013e318214f33a

Lemke J, Barth T F, Juchems M, Kapapa T, Henne-Bruns D, Kornmann M. 2011. Long-term survival following resection of brain metastases from pancreatic cancer. Anticancer Res  31(12): p. 4599-603 https://www.ncbi.nlm.nih.gov/pubmed/22199336.

Chen G, Tian X, Liu Z, Zhou S, Schmidt B, Henne-Bruns D, Bachem M, Kornmann M. 2010. Inhibition of endogenous SPARC enhances pancreatic cancer cell growth: modulation by FGFR1-III isoform expression. Br J Cancer  102(1): p. 188-95 https://www.ncbi.nlm.nih.gov/pubmed/19920824. 10.1038/sj.bjc.6605440

Kalbitz M, Liener U, Kornmann M, Gebhard F, Huber-Lang M. 2010. [Evaluation of an objective structured clinical examination (OSCE) in surgery and orthopedics by medical students]. Unfallchirurg  113(9): p. 726-30, 732-3 https://www.ncbi.nlm.nih.gov/pubmed/20700572. 10.1007/s00113-009-1690-2

Kornmann M, Staib L, Wiegel T, Kreuser E D, Kron M, Baumann W, Henne-Bruns D, Link K H. 2010. Adjuvant chemoradiotherapy of advanced resectable rectal cancer: results of a randomised trial comparing modulation of 5-fluorouracil with folinic acid or with interferon-alpha. Br J Cancer  103(8): p. 1163-72 https://www.ncbi.nlm.nih.gov/pubmed/20877353. 10.1038/sj.bjc.6605871

Link K H, Kornmann M, Bittner R, Kockerling F, Arbogast R, Gastinger I, Heitland W, Henne-Bruns D, Lang H, Lippert H, Mann M, Meyer H J, Polonius M J, Post S, Raab R, Schiedeck T, Schumpelick V. 2010. [Quality criteria for treatment of colorectal cancer. From a surgeon's viewpoint]. Chirurg  81(3): p. 222-30 https://www.ncbi.nlm.nih.gov/pubmed/19760377. 10.1007/s00104-009-1796-7

Scheele J, Barth T F, Strassburg J, Juchems M, Kornmann M, Henne-Bruns D. 2010. Dermoid cyst of the pancreas. Int J Colorectal Dis  25(3): p. 415-6 https://www.ncbi.nlm.nih.gov/pubmed/19802626. 10.1007/s00384-009-0811-2

Song B, Wang Y, Titmus M A, Botchkina G, Formentini A, Kornmann M, Ju J. 2010. Molecular mechanism of chemoresistance by miR-215 in osteosarcoma and colon cancer cells. Mol Cancer  9: p. 96 https://www.ncbi.nlm.nih.gov/pubmed/20433742. 10.1186/1476-4598-9-96

Buttenschoen K, Schneider M E, Utz K, Kornmann M, Beger H G, Carli Buttenschoen D. 2009. Effect of major abdominal surgery on endotoxin release and expression of Toll-like receptors 2/4. Langenbecks Arch Surg  394(2): p. 293-302 https://www.ncbi.nlm.nih.gov/pubmed/18546014. 10.1007/s00423-008-0357-8

Formentini A, Prokopchuk O, Strater J, Kleeff J, Grochola L F, Leder G, Henne-Bruns D, Korc M, Kornmann M. 2009. Interleukin-13 exerts autocrine growth-promoting effects on human pancreatic cancer, and its expression correlates with a propensity for lymph node metastases. Int J Colorectal Dis  24(1): p. 57-67 https://www.ncbi.nlm.nih.gov/pubmed/18758789. 10.1007/s00384-008-0550-9

Juchems M S, Ernst A S, Kornmann M, Barth T F, Kramer K, Brambs H J, Aschoff A J. 2009. Value of MDCT in preoperative local staging of rectal cancer for predicting the necessity for neoadjuvant radiochemotherapy. Rofo  181(12): p. 1168-74 https://www.ncbi.nlm.nih.gov/pubmed/19408213. 10.1055/s-0028-1109356

Siech M, Zhou Z, Zhou S, Bair B, Alt A, Hamm S, Gross H, Mayer J, Beger H G, Tian X, Kornmann M, Bachem M G. 2009. Stimulation of stellate cells by injured acinar cells: a model of acute pancreatitis induced by alcohol and fat (VLDL). Am J Physiol Gastrointest Liver Physiol  297(6): p. G1163-71 https://www.ncbi.nlm.nih.gov/pubmed/19779015. 10.1152/ajpgi.90468.2008

Song B, Wang Y, Xi Y, Kudo K, Bruheim S, Botchkina G I, Gavin E, Wan Y, Formentini A, Kornmann M, Fodstad O, Ju J. 2009. Mechanism of chemoresistance mediated by miR-140 in human osteosarcoma and colon cancer cells. Oncogene  28(46): p. 4065-74 https://www.ncbi.nlm.nih.gov/pubmed/19734943. 10.1038/onc.2009.274

Buttenschoen K, Kornmann M, Berger D, Leder G, Beger H G, Vasilescu C. 2008. Endotoxemia and endotoxin tolerance in patients with ARDS. Langenbecks Arch Surg  393(4): p. 473-8 https://www.ncbi.nlm.nih.gov/pubmed/18320210. 10.1007/s00423-008-0317-3

Chen G, Wang J, Liu Z, Kornmann M. 2008. Exon III splicing of fibroblast growth factor receptor 1 is modulated by growth factors and cyclin D1. Pancreas  37(2): p. 159-64 https://www.ncbi.nlm.nih.gov/pubmed/18665077. 10.1097/MPA.0b013e31816618a4

Kornmann M, Formentini A, Ette C, Henne-Bruns D, Kron M, Sander S, Baumann W, Kreuser E D, Staib L, Link K H. 2008. Prognostic factors influencing the survival of patients with colon cancer receiving adjuvant 5-FU treatment. Eur J Surg Oncol  34(12): p. 1316-21 https://www.ncbi.nlm.nih.gov/pubmed/18313881. 10.1016/j.ejso.2008.01.019

Kornmann MHenne-Bruns D. 2008. [Quality for the data basis of evidence-based medicine: rectal cancer and preoperative 5 x 5 irradiation]. Zentralbl Chir  133(1): p. 20-4 https://www.ncbi.nlm.nih.gov/pubmed/18278697. 10.1055/s-2008-1004663

Kornmann M, Henne-Bruns D, Porzsolt F. 2008. Neoadjuvant treatment of rectal carcinoma: assessment of health care services by physicians and lay persons. J Clin Oncol  26(30): p. 4866-8 https://www.ncbi.nlm.nih.gov/pubmed/18711174. 10.1200/JCO.2008.16.2891

Kornmann M, Porzsolt F, Henne-Bruns D. 2008. [Lay assessment of health care services using therapy for rectal cancer as an example]. Zentralbl Chir  133(2): p. 148-55 https://www.ncbi.nlm.nih.gov/pubmed/18415902. 10.1055/s-2008-1004772

Xi Y, Formentini A, Nakajima G, Kornmann M, Ju J. 2008. Validation of biomarkers associated with 5-fluorouracil and thymidylate synthase in colorectal cancer. Oncol Rep  19(1): p. 257-62 https://www.ncbi.nlm.nih.gov/pubmed/18097604.

Formentini A, Sander S, Denzer S, Straeter J, Henne-Bruns D, Kornmann M. 2007. Thymidylate synthase expression in resectable and unresectable pancreatic cancer: role as predictive or prognostic marker? Int J Colorectal Dis  22(1): p. 49-55 https://www.ncbi.nlm.nih.gov/pubmed/16538493. 10.1007/s00384-006-0111-z

Liu Z, Ishiwata T, Zhou S, Maier S, Henne-Bruns D, Korc M, Bachem M, Kornmann M. 2007. Human fibroblast growth factor receptor 1-IIIb is a functional fibroblast growth factor receptor expressed in the pancreas and involved in proliferation and movement of pancreatic ductal cells. Pancreas  35(2): p. 147-57 https://www.ncbi.nlm.nih.gov/pubmed/17632321. 10.1097/mpa.0b013e318053e7e3

Liu Z, Neiss N, Zhou S, Henne-Bruns D, Korc M, Bachem M, Kornmann M. 2007. Identification of a fibroblast growth factor receptor 1 splice variant that inhibits pancreatic cancer cell growth. Cancer Res  67(6): p. 2712-9 https://www.ncbi.nlm.nih.gov/pubmed/17363592. 10.1158/0008-5472.CAN-06-3843

Liu Z B, Yang Y M, Qiao Q L, Wan Y L, Kornmann M, Huang Y T. 2006. [The role of human fibroblast growth factor receptor 1-IIIb isoform in proliferation of pancreatic ductal cells and its effects to mitogen-activated protein kinase]. Zhonghua Yi Xue Za Zhi  86(40): p. 2812-6 https://www.ncbi.nlm.nih.gov/pubmed/17200012.

Xi Y, Formentini A, Chien M, Weir D B, Russo J J, Ju J, Kornmann M, Ju J. 2006. Prognostic Values of microRNAs in Colorectal Cancer. Biomark Insights  2: p. 113-121 https://www.ncbi.nlm.nih.gov/pubmed/18079988.

Hofmann C, Buttenschoen K, Straeter J, Henne-Bruns D, Kornmann M. 2005. Pre-clinical evaluation of the activity of irinotecan as a basis for regional chemotherapy. Anticancer Res  25(2A): p. 795-804 https://www.ncbi.nlm.nih.gov/pubmed/15868911.

Link K H, Kornmann M, Staib L, Redenbacher M, Kron M, Beger H G, Study Group Oncology of Gastrointestinal T. 2005. Increase of survival benefit in advanced resectable colon cancer by extent of adjuvant treatment: results of a randomized trial comparing modulation of 5-FU + levamisole with folinic acid or with interferon-alpha. Ann Surg  242(2): p. 178-87 https://www.ncbi.nlm.nih.gov/pubmed/16041207. 10.1097/01.sla.0000171033.65639.a9

Link K H, Sagban T A, Morschel M, Tischbirek K, Holtappels M, Apell V, Zayed K, Kornmann M, Staib L. 2005. Colon cancer: survival after curative surgery. Langenbecks Arch Surg  390(2): p. 83-93 https://www.ncbi.nlm.nih.gov/pubmed/15455234. 10.1007/s00423-004-0508-5

Prokopchuk O, Liu Y, Henne-Bruns D, Kornmann M. 2005. Interleukin-4 enhances proliferation of human pancreatic cancer cells: evidence for autocrine and paracrine actions. Br J Cancer  92(5): p. 921-8 https://www.ncbi.nlm.nih.gov/pubmed/15714203. 10.1038/sj.bjc.6602416

Formentini A, Henne-Bruns D, Kornmann M. 2004. Thymidylate synthase expression and prognosis of patients with gastrointestinal cancers receiving adjuvant chemotherapy: a review. Langenbecks Arch Surg  389(5): p. 405-13 https://www.ncbi.nlm.nih.gov/pubmed/15309542. 10.1007/s00423-004-0510-y

Hillenbrand A, Formentini A, Staib L, Sander S, Salonga D, Danenberg K, Danenberg P, Kornmann M. 2004. A longterm follow-up study of thymidylate synthase as a predictor for survival of patients with liver tumours receiving hepatic arterial infusion chemotherapy. Eur J Surg Oncol  30(4): p. 407-13 https://www.ncbi.nlm.nih.gov/pubmed/15063894. 10.1016/j.ejso.2004.01.012

Guthoff I, Lotspeich E, Fester C, Wallin I, Schatz M, Ehrsson H, Kornmann M. 2003. Hepatic artery infusion using oxaliplatin in combination with 5-fluorouracil, folinic acid and mitomycin C: oxaliplatin pharmacokinetics and feasibility. Anticancer Res  23(6D): p. 5203-8 https://www.ncbi.nlm.nih.gov/pubmed/14981990.

Kornmann M, Beger H G, Link K H. 2003. Chemosensitivity testing and test-directed chemotherapy in human pancreatic cancer. Recent Results Cancer Res  161: p. 180-95 https://www.ncbi.nlm.nih.gov/pubmed/12528808. 10.1007/978-3-642-19022-3_15

Kornmann M, Schwabe W, Sander S, Kron M, Strater J, Polat S, Kettner E, Weiser H F, Baumann W, Schramm H, Hausler P, Ott K, Behnke D, Staib L, Beger H G, Link K H. 2003. Thymidylate synthase and dihydropyrimidine dehydrogenase mRNA expression levels: predictors for survival in colorectal cancer patients receiving adjuvant 5-fluorouracil. Clin Cancer Res  9(11): p. 4116-24 https://www.ncbi.nlm.nih.gov/pubmed/14519634.

Kornmann M, Ishiwata T, Matsuda K, Lopez M E, Fukahi K, Asano G, Beger H G, Korc M. 2002. IIIc isoform of fibroblast growth factor receptor 1 is overexpressed in human pancreatic cancer and enhances tumorigenicity of hamster ductal cells. Gastroenterology  123(1): p. 301-13 https://www.ncbi.nlm.nih.gov/pubmed/12105858. 10.1053/gast.2002.34174

Kornmann MLink K H. 2002. Conversion of locally inoperable primary rectal cancer with multiple liver metastases to an option for cure after local down-staging and hepatic arterial infusion chemotherapy. Langenbecks Arch Surg  387(2): p. 90-3 https://www.ncbi.nlm.nih.gov/pubmed/12111261. 10.1007/s00423-002-0295-9

Kornmann M, Link K H, Galuba I, Ott K, Schwabe W, Hausler P, Scholz P, Strater J, Polat S, Leibl B, Kettner E, Schlichting C, Baumann W, Schramm H, Hecker U, Ridwelski K, Vogt J H, Zerbian K U, Schutze F, Kreuser E D, Behnke D, Beger H G. 2002. Association of time to recurrence with thymidylate synthase and dihydropyrimidine dehydrogenase mRNA expression in stage II and III colorectal cancer. J Gastrointest Surg  6(3): p. 331-7 https://www.ncbi.nlm.nih.gov/pubmed/12022983. 10.1016/s1091-255x(02)00018-5

Strater J, Walczak H, Pukrop T, Von Muller L, Hasel C, Kornmann M, Mertens T, Moller P. 2002. TRAIL and its receptors in the colonic epithelium: a putative role in the defense of viral infections. Gastroenterology  122(3): p. 659-66 https://www.ncbi.nlm.nih.gov/pubmed/11874999. 10.1053/gast.2002.31889

Kornmann M, Lopez M, Beger H, Korc M. 2001. Expression of the IIIc Variant of FGF Receptor-1 Confers Mitogenic Responsiveness to Heparin and FGF-5 in TAKA-1 Pancreatic Ductal Cells. Int J Gastrointest Cancer  29(2): p. 85-92 https://www.ncbi.nlm.nih.gov/pubmed/12754391.

Kornmann M, Lopez M E, Beger H G, Korc M. 2001. Expression of the IIIc variant of FGF receptor-1 confers mitogenic responsiveness to heparin and FGF-5 in TAKA-1 pancreatic ductal cells. Int J Pancreatol  29(2): p. 85-92 https://www.ncbi.nlm.nih.gov/pubmed/11876253. 10.1385/IJGC:29:2:085

Link K H, Staib L, Kornmann M, Formentini A, Schatz M, Suhr P, Messer P, Rottinger E, Beger H G, Forschungsgruppe Onkologie Gastrointestinale T. 2001. Surgery, radio- and chemotherapy for multimodal treatment of rectal cancer. Swiss Surg  7(6): p. 256-74 https://www.ncbi.nlm.nih.gov/pubmed/11771444. 10.1024/1023-9332.7.6.256

Link K H, Sunelaitis E, Kornmann M, Schatz M, Gansauge F, Leder G, Formentini A, Staib L, Pillasch J, Beger H G. 2001. Regional chemotherapy of nonresectable colorectal liver metastases with mitoxantrone, 5-fluorouracil, folinic acid, and mitomycin C may prolong survival. Cancer  92(11): p. 2746-53 https://www.ncbi.nlm.nih.gov/pubmed/11753947. 10.1002/1097-0142(20011201)92:11<2746::aid-cncr10098>3.0.co;2-q

Itakura J, Ishiwata T, Shen B, Kornmann M, Korc M. 2000. Concomitant over-expression of vascular endothelial growth factor and its receptors in pancreatic cancer. Int J Cancer  85(1): p. 27-34 https://www.ncbi.nlm.nih.gov/pubmed/10585578. 10.1002/(sici)1097-0215(20000101)85:1<27::aid-ijc5>3.0.co;2-8

Kleeff J, Kornmann M, Sawhney H, Korc M. 2000. Actinomycin D induces apoptosis and inhibits growth of pancreatic cancer cells. Int J Cancer  86(3): p. 399-407 https://www.ncbi.nlm.nih.gov/pubmed/10760829. 10.1002/(sici)1097-0215(20000501)86:3<399::aid-ijc15>3.0.co;2-g

Kornmann M, Butzer U, Blatter J, Beger H G, Link K H. 2000. Pre-clinical evaluation of the activity of gemcitabine as a basis for regional chemotherapy of pancreatic and colorectal cancer. Eur J Surg Oncol  26(6): p. 583-7 https://www.ncbi.nlm.nih.gov/pubmed/11034810. 10.1053/ejso.2000.0951

Kornmann M, Fakler H, Butzer U, Beger H G, Link K H. 2000. Oxaliplatin exerts potent in vitro cytotoxicity in colorectal and pancreatic cancer cell lines and liver metastases. Anticancer Res  20(5A): p. 3259-64 https://www.ncbi.nlm.nih.gov/pubmed/11062751.

Kornmann M, Ishiwata T, Kleeff J, Beger H G, Korc M. 2000. Fas and Fas-ligand expression in human pancreatic cancer. Ann Surg  231(3): p. 368-79 https://www.ncbi.nlm.nih.gov/pubmed/10714630. 10.1097/00000658-200003000-00010

Kornmann M, Ishiwata T, Maruyama H, Beger H G, Korc M. 2000. Coexpression of FAS and FAS-ligand in chronic pancreatitis: correlation with apoptosis. Pancreas  20(2): p. 123-8 https://www.ncbi.nlm.nih.gov/pubmed/10707926. 10.1097/00006676-200003000-00003

Leder G H, Pillasch J, Kornmann M, Danenberg P V, Link K H. 2000. Theoretical considerations and in vitro concentration response studies with two human colorectal carcinoma cell lines. The rational experimental base for clinical studies in regional chemotherapy. Gan To Kagaku Ryoho  27(4): p. 565-77 https://www.ncbi.nlm.nih.gov/pubmed/10790999.

Link K H, Kornmann M, Butzer U, Leder G, Sunelaitis E, Pillasch J, Salonga D, Danenberg K D, Danenberg P V, Beger H G. 2000. Thymidylate synthase quantitation and in vitro chemosensitivity testing predicts responses and survival of patients with isolated nonresectable liver tumors receiving hepatic arterial infusion chemotherapy. Cancer  89(2): p. 288-96 https://www.ncbi.nlm.nih.gov/pubmed/10918158.

Kornmann M, Danenberg K D, Arber N, Beger H G, Danenberg P V, Korc M. 1999. Inhibition of cyclin D1 expression in human pancreatic cancer cells is associated with increased chemosensitivity and decreased expression of multiple chemoresistance genes. Cancer Res  59(14): p. 3505-11 https://www.ncbi.nlm.nih.gov/pubmed/10416617.

Kornmann M, Kleeff J, Debinski W, Korc M. 1999. Pancreatic cancer cells express interleukin-13 and -4 receptors, and their growth is inhibited by Pseudomonas exotoxin coupled to interleukin-13 and -4. Anticancer Res  19(1A): p. 125-31 https://www.ncbi.nlm.nih.gov/pubmed/10226533.

Kornmann M, Tangvoranuntakul P, Korc M. 1999. TGF-beta-1 up-regulates cyclin D1 expression in COLO-357 cells, whereas suppression of cyclin D1 levels is associated with down-regulation of the type I TGF-beta receptor. Int J Cancer  83(2): p. 247-54 https://www.ncbi.nlm.nih.gov/pubmed/10471535. 10.1002/(sici)1097-0215(19991008)83:2<247::aid-ijc17>3.0.co;2-0

Link K H, Kornmann M, Formentini A, Leder G, Sunelaitis E, Schatz M, Pressmar J, Beger H G. 1999. Regional chemotherapy of non-resectable liver metastases from colorectal cancer - literature and institutional review. Langenbecks Arch Surg  384(4): p. 344-53 https://www.ncbi.nlm.nih.gov/pubmed/10473854. 10.1007/s004230050212

Link K H, Kornmann M, Leder G, Pillasch A F, Sunelaitis E, Schatz M, Pressmar J, Beger H G. 1999. Basic research supported developments of chemotherapy in nonresectable isolated colorectal liver metastases to a protocol of hepatic artery infusion using mitoxantrone, 5-FU + folinic acid and mitomycin C. Gan To Kagaku Ryoho  26(3): p. 269-81 https://www.ncbi.nlm.nih.gov/pubmed/10065089.

Link K H, Leder G, Formentini A, Fortnagel G, Kornmann M, Schatz M, Beger H G. 1999. Surgery and multimodal treatments in pancreatic cancer--a review on the basis of future multimodal treatment concepts. Gan To Kagaku Ryoho  26(1): p. 10-40 https://www.ncbi.nlm.nih.gov/pubmed/9987495.

Link K H, Pillasch J, Formentini A, Sunelaitis E, Leder G, Safi F, Kornmann M, Beger H G. 1999. Downstaging by regional chemotherapy of non-resectable isolated colorectal liver metastases. Eur J Surg Oncol  25(4): p. 381-8 https://www.ncbi.nlm.nih.gov/pubmed/10419708. 10.1053/ejso.1999.0661

Ishiwata T, Kornmann M, Beger H G, Korc M. 1998. Enhanced fibroblast growth factor 5 expression in stromal and exocrine elements of the pancreas in chronic pancreatitis. Gut  43(1): p. 134-9 https://www.ncbi.nlm.nih.gov/pubmed/9771418. 10.1136/gut.43.1.134

Kornmann M, Arber N, Korc M. 1998. Inhibition of basal and mitogen-stimulated pancreatic cancer cell growth by cyclin D1 antisense is associated with loss of tumorigenicity and potentiation of cytotoxicity to cisplatinum. J Clin Invest  101(2): p. 344-52 https://www.ncbi.nlm.nih.gov/pubmed/9435306. 10.1172/JCI1323

Kornmann M, Beger H G, Korc M. 1998. Role of fibroblast growth factors and their receptors in pancreatic cancer and chronic pancreatitis. Pancreas  17(2): p. 169-75 https://www.ncbi.nlm.nih.gov/pubmed/9700949. 10.1097/00006676-199808000-00010

Kornmann M, Ishiwata T, Arber N, Beger H G, Korc M. 1998. Increased cyclin D1 expression in chronic pancreatitis. Pancreas  17(2): p. 158-62 https://www.ncbi.nlm.nih.gov/pubmed/9700947. 10.1097/00006676-199808000-00008

Kornmann M, Ishiwata T, Itakura J, Tangvoranuntakul P, Beger H G, Korc M. 1998. Increased cyclin D1 in human pancreatic cancer is associated with decreased postoperative survival. Oncology  55(4): p. 363-9 https://www.ncbi.nlm.nih.gov/pubmed/9663429. 10.1159/000011879

Kornmann M, Maruyama H, Bergmann U, Tangvoranuntakul P, Beger H G, White M F, Korc M. 1998. Enhanced expression of the insulin receptor substrate-2 docking protein in human pancreatic cancer. Cancer Res  58(19): p. 4250-4 https://www.ncbi.nlm.nih.gov/pubmed/9766646.

Link K H, Leder G, Pillasch J, Butzer U, Staib L, Kornmann M, Bruckner U, Beger H G. 1998. In vitro concentration response studies and in vitro phase II tests as the experimental basis for regional chemotherapeutic protocols. Semin Surg Oncol  14(3): p. 189-201 https://www.ncbi.nlm.nih.gov/pubmed/9548601. 10.1002/(sici)1098-2388(199804/05)14:3<189::aid-ssu2>3.0.co;2-4

Ishiwata T, Bergmann U, Kornmann M, Lopez M, Beger H G, Korc M. 1997. Altered expression of insulin-like growth factor II receptor in human pancreatic cancer. Pancreas  15(4): p. 367-73 https://www.ncbi.nlm.nih.gov/pubmed/9361090. 10.1097/00006676-199711000-00006

Kornmann M, Ishiwata T, Beger H G, Korc M. 1997. Fibroblast growth factor-5 stimulates mitogenic signaling and is overexpressed in human pancreatic cancer: evidence for autocrine and paracrine actions. Oncogene  15(12): p. 1417-24 https://www.ncbi.nlm.nih.gov/pubmed/9333017. 10.1038/sj.onc.1201307

Kornmann M, Link K H, Lenz H J, Pillasch J, Metzger R, Butzer U, Leder G H, Weindel M, Safi F, Danenberg K D, Beger H G, Danenberg P V. 1997. Thymidylate synthase is a predictor for response and resistance in hepatic artery infusion chemotherapy. Cancer Lett  118(1): p. 29-35 https://www.ncbi.nlm.nih.gov/pubmed/9310257. 10.1016/s0304-3835(97)00220-6

Bergmann U, Funatomi H, Kornmann M, Beger H G, Korc M. 1996. Increased expression of insulin receptor substrate-1 in human pancreatic cancer. Biochem Biophys Res Commun  220(3): p. 886-90 https://www.ncbi.nlm.nih.gov/pubmed/8607861. 10.1006/bbrc.1996.0500

Bergmann U, Funatomi H, Kornmann M, Ishiwata T, Beger H, Korc M. 1996. Insulin-like growth factor II activates mitogenic signaling in pancreatic cancer cells via IRS-1. Int J Oncol  9(3): p. 487-92 https://www.ncbi.nlm.nih.gov/pubmed/21541539. 10.3892/ijo.9.3.487

Link K H, Kornmann M, Leder G H, Butzer U, Pillasch J, Staib L, Gansauge F, Beger H G. 1996. Regional chemotherapy directed by individual chemosensitivity testing in vitro: a prospective decision-aiding trial. Clin Cancer Res  2(9): p. 1469-74 https://www.ncbi.nlm.nih.gov/pubmed/9816322.

Deutsche Gesellschaft für Chirurgie (DGC)

Deutsche Gesellschaft für Viszeralchirurgie (DGVC)

Deutsche Krebsgesellschaft 

European Society of Surgical Oncology (ESSO) A

International Colorectal Cancer Club (ICRCC)

Vereinigung Mittelrheinischer Chirurgen

Süddeutsche Gesellschaft für Gastroenterologie

Deutsche Gesellschaft für Plastische und Wiederherstellungschirurgie (DGPW)

Präsident des ICRCC (seit 2018)