Sektion für Neuropsychologie und Funktionelle Bildgebung

Team

Profilbild von Prof. Dr. phil. Dipl.-Psych. Georg Grön

Prof. Dr. phil. Dipl.-Psych. Georg Grön

Leiter Sektion Neurophysiologie und Funktionelle Bildgebung

Kathrin Brändle

Dipl.-Biol. Filip Niemann

Dr. biol. hum. Martin Ulrich

 

Die Sektion wurde 2004 zeitgleich mit der Inbetriebnahme des ersten Magnetresonanztomographen (MRT) an der Ulmer Universitätsklinik für Psychiatrie und Psychotherapie eingerichtet. Der damalige 3-Tesla Nur-Kopf MRT (Siemens MAGNETOM Allegra) war im Rahmen eines Forschungs-HBFG-Verfahrens durch die Deutsche Forschungsgemeinschaft (DFG) finanziert worden. Zwischenzeitlich wurde dieses Gerät durch ein 3-Tesla Siemens MAGNETOM Prisma ersetzt, das im Rahmen eines 91b-GG Verfahrens jeweils hälftig durch die DFG und das Land Baden-Württemberg finanziert wurde. Dieses Gerät steht seit November 2014 als Core Facility für bildgebende neurowissenschaftliche Forschung zur Verfügung und wird von Mitarbeitern der Sektion für Neuropsychologie und Funktionelle Bildgebung verwaltet.

 

Technik/Methoden

  • 3-Tesla MRT (Siemens MAGNETOM Prisma) finanziert durch die DFG und das Land Baden-Württemberg
  • Visuelle, akustische und haptische Stimulation für funktionelle Bildgebung
  • MRT-kompatible Verhaltensprotokollierung und Hautleitfähigkeitsmessung
  • Messplätze für klinische und experimentelle neuropsychologische Untersuchungen
  • Statistische Analyse von experimentellen MRT- und Verhaltensdaten

 

Forschung

Im Feld der klinisch-kognitiven Neurowissenschaft verwenden wir als Methode die funktionelle und strukturelle MRT-Bildgebung bei der Untersuchung und Erforschung von Hirnfunktionen des Menschen unter definierten neuropsychologischen Anforderungen. Im Vordergrund stehen zentrale psychische Prozesse und deren pathologische Veränderungen hinsichtlich der Auslösung und Aufrechterhaltung psychiatrischer Erkrankungen. Ausgehend von ihrer normalen Funktion versuchen wir, diese Prozesse unter experimentelle Kontrolle zu bringen und unter den Erfordernissen der funktionellen MRT-Bildgebung messbar zu machen.

 

Lehre und Fortbildung

  • Wahlpflichtveranstaltungen zur funktionellen Magnetresonanztomographie
  • Wahlpflichtveranstaltungen zu  Kognitiven Neurowissenschaften in der Psychiatrie
  • Journal Clubs zu ausgewählten aktuellen Forschungsthemen im Bereich der bildgebenden Neurowissenschaften am Menschen

 

Publikationen

2005

Abler B, Erk S, Walter H (2005) Das menschliche Belohnungssystem - Erkenntnisse der funktionellen Bildgebung und klinische Implikationen. Nervenheilkunde 24: 167-76.

Abler B, Walter H, Erk S (2005) Neural Correlates of Frustration. Neuroreport 16: 669-72.

Beschoner P, Riecker A, Viviani R (2005) Magnetresonanztomographische Befunde bei Patienten mit Schizophrenie. Nervenheilkunde 24: 190-7.

Bittner D, Grön G (2005) Morbus Alzheimer - Diagnostik und Therapie. Nervenheilkunde 24: 591-600.

Erk S, Martin S, Walter H (2005) Emotional context during encoding of neural items modulates brain activation not only during encoding but also during recognition. Neuroimage 26: 829-38.

Grön G, Kirstein M, Thielscher A, Riepe MW, Spitzer M (2005) Cholinergic enhancement of episodic memory in healthy young adults. Psychopharmacology 182: 170-9.

Grön G, Riepe MW (2005) Funktionelle Magnetresonanztomographie zur Frühdiagnostik der Alzheimer-Demenz. In: Walter H (Hrsg). Funktionelle Bildgebung in Psychiatrie und Psychotherapie. Methodische Grundlagen und klinische Anwendungen. Schattauer Verlag, Stuttgart. 195ff

Ruchsow M, Spitzer M, Grön G, Grothe J, Kiefer M (2005) Error processing and impulsiveness in normals: evidence from event-related potentials. Brain Res Cogn Brain Res 24: 317-25.

Ruchsow M, Grön G, Reuter K, Spitzer M, Hermle L, Kiefer M (2005) Electrophysiological correlates of error processing in patients with obsessive-compulsive disorder. J Psychophysiol 19: 298-304.

Schmitz BL, Aschoff AJ, Hoffmann MH, Grön G (2005) Advantages and pitfalls in 3T MR brain imaging: a pictorial review. Am J Neuroradiol  26: 2229-37.

Schmitz BL, Grön G, Brausewetter F, Hoffmann MH, Aschoff AJ (2005) Enhancing gray-to-white matter contrast in 3T T1 spin-echo brain scans by optimizing flip angle. Am J Neuroradiol 26: 2000-4.

Vasic N, Wolf RC, Walter H (2005) Neurofunktionelle Grundlagen unipolarer depressiver Störungen. Nervenheilkunde 24: 603-10.

Viviani R, Grön G, Spitzer M (2005) Functional principal component analysis of fMRI data. Hum Brain Mapp 24: 109-29.

Wolf RC (2005) Kognitive Defizite in der Schizophrenie: Zwischen präfrontaler Dysfunktion und funktioneller Entkopplung. Nervenheilkunde 24: 573-83.

Wolf RC, Walter H (2005) Evaluation of a novel event-related parametric fMRI paradigm investigating prefrontal function. Psychiat Res 140: 73-83.

Spitzer M, Rath F, Grön G (2005) Musik und Befindlichkeit. Nervenheilkunde  24: 198-202.

Beinhoff U, Hilbert V, Bittner D, Grön G, Riepe MW (2005) Screening for cognitive impairment: a triage for outpatient care. Dement Geriatr Cogn  20: 278-85.

 

2006

Abler B, Roebroeck A, Goebel R, Höse A, Schönfeldt-Lecuona C, Hole G, Walter H (2006) Investigating directed influences between activated brain areas in  a motor-response task using fMRI. Magn Reson Imaging 24: 181-5.

Abler B, Walter H, Erk S, Kammerer H, Spitzer M (2006) Prediction error as a linear function of reward probability is coded in human nucleus accumbens. Neuroimage 31: 790-5.

Buchheim A, Erk S, George C, Kächele H, Ruchsow M, Spitzer M, Kircher T, Walter H (2006) Measuring Attachment Representation in an fMRI Environment : A Pilot Study. Psychopathology 39: 144-52.

Buchheim A, George C, Kächele H, Erk S, Walter H. (2006) Measuring adult attachment representation in an fMRI environment: concepts and assessment. Psychopathology  39: 136-43.

Erk S, Abler B, Walter H (2006) Cognitive modulation of emotion anticipation. Eur J Neurosci 24: 1227-36.

Freudenmann RW, Schönfeldt-Lecuona C, Spitzer M, Hermle L ,Grön G  (2006) Electroconvulsive therapy in the treatment of depression in a former Ecstasy user. J Psychopharmacol  20: 860-2.

Grön G, Brandenburg I, Wunderlich AP, Riepe MW (2006) Inhibition of hippocampal function in mild cognitive impairment: targeting the cholineric hypothesis. Neurobiol Aging 27: 78-87.

Ruchsow M, Herrnberger B, Beschoner P, Grön G, Spitzer M, Kiefer M (2006) Error processing in major depressive disorder: Evidence from event related potentials. J Psychiatr Res 40: 37-46.

Ruchsow M, Walter H, Buchheim A, Martius P, Spitzer M, Kächele H, Grön G, Kiefer M (2006) Error-related negativity and response evaluation in patients with borderline personality disorder. Biol Psychol 72: 133-40.

Wolf R, Schönfeldt-Lecuona C (2006) Depressive symptoms as first manifestation of posterior cortical atrophy. Am J Psychiat 163: 939-40.

Wolf R, Vasic N, Walter H (2006) Differential activation of ventrolateral prefrontal cortex during working memory retrieval. Neuropsychologia 44: 2558-63.

Wolf R, Vasic N, Walter H (2006) The concept of working memory in schizophrenia: current evidence and future perspectives. Fortschr Neurol Psyc 74: 449-68.

 

2007

Abler B, Erk S, Herwig U, Walter H (2007) Anticipation of aversive stimuli activates extended amygdala in unipolar depression. J Psychiatr Res 41: 511-22.

Abler B, Vasic N (2007) Neue Erkenntnisse über die Rolle des zentralen dopaminergen Systems bei psychiatrischen Erkrankungen - Schizophrenie, Depression, Manie und ADHS. Nervenheilkunde 26: 141-9.

Abler B, Erk S, Walter H (2007) Human reward system activation is modulated by a single dose of olanzapine in healthy subjects in an event-related, double-blind, placebo-controlled fMRI study. Psychopharmacology 191: 823-33.

Herwig U, Abler B, Walter H, Erk S (2007) Expecting unpleasant stimuli- An fMRI study. Psychiat Res 154: 1-12.

Herwig U, Baumgärtner T, Kaffenberger T, Brühl A, Kottlow M, Schreiter-Gasser U, Abler B, Jäncke L, Rufer M (2007) Modulation of anticipatory emotion and perception processing by cognitive control. Neuroimage 37: 652-62.

Kammer T, Vorwerg M, Herrnberger B (2007) Anisotropy in the visual cortex investigated by neuronavigated transcranial magnetic stimulation. Neuroimage 36: 313-21.

Riecker A, Ackermann H, Schmitz B, Kassubek J, Herrnberger B, Steinbrink C (2007) Bilateral language function in callosal agenesis: An fMRI and DTI study.  J Neurol 254: 528-30.

Spitzer M, Fischbacher U, Herrnberger B, Grön G, Fehr E (2007) The Neural Signature of Social Norm Compliance. Neuron 56: 185-96.

Vasic N, Wolf RC, Walter H (2007) Exekutive Funktionen bei depressiven Patienten: Zur Rolle der präfrontalen Aktivierung.  Nervenarzt 78: 628-40.

Walter H, Wolf RC, Spitzer M, Vasic N (2007) Inreased left prefrontal activation in patients with unipolar depression: An event-related, parametric, performance-controlled fMRI study. J Affect Disorders 101: 175-85.

Walter H, Vasic N, Höse A, Spitzer M, Wolf RC (2007) Working memory dysfunction in schizophrenia compared to healthy controls and patients with depression: Evidence from event-related fMRI. Neuroimage 35: 1551-61.

Viviani R, Beschoner P, Ehrhard K, Schmitz B, Thöne J (2007) Non-normality and transformations of random fields, with an application to voxel-based morphometry. Neuroimage 35: 121-30.

Viviani R, Beschoner P, Jaeckle T, Hipp P, Kassubek J, Schmitz B (2007) The bootstrap and cross-validation in neuroimaging applications: Estimation of the distribution of extrema of random fields for single volume tests, with an application to ADC maps. Hum Brain Mapp 28: 1075-88.

Wolf RC, Vasic N, Höse A, Spitzer M, Walter H (2007) Changes over time in frontotemporal activation during a working memory task in patients with schizophrenia. Schizophr Res 91: 141-50.

Wolf RC, Vasic N, Schönfeldt-Lecuona C, Landwehrmeyer G, Ecker D (2007) Dorsolateral prefrontal cortex dysfunction in presymptomatic Huntington's disease: evidence from event-related fMRI. Brain 130: 2845-57.

Wunderlich AP, Grön G, Braun V (2007) Functional MR imaging of working memory before neurosurgery. Z Med Phys. 17: 250-7.
 

2008

Abler B, Greenhouse I, Ongur D, Walter H, Heckers S (2008) Abnormal Reward System Activation in Mania. Neuropsychopharmacol 33: 2217-27.

Abler B, Hofer C, Viviani R (2008) Habitual emotion regulation strategies and baseline brain perfusion. Neuroreport 19: 21-4.

Beschoner P, Richter S, Lo H, Sim EJ, Baron K, Osterfeld N, Horn AB, Viviani R (2008) Baseline brain perfusion and working memory capacity: a neuroimaging study. Neuroreport 19: 1803-7.

Buchheim A, Erk S, George C, Kächele H, Kircher T, Martius P, Pokorny D, Ruchsow M, Spitzer M, Walter H (2008) Neural correlates of attachment trauma in borderline personality disorder: a functional magnetic resonance imaging study. Psychiat Res 163: 223-35.

Hönig K, Sim EJ, Bochev V, Herrnberger B, Kiefer M (2008) Conceptual Flexibility in the Human Brain: Dynamic Recruitment of Semantic Maps from Visual, Motor, and Motion-related Areas. J Cognitive Neurosci 20: 1799-1814.

Kiefer M, Sim EJ, Herrnberger B, Grothe J, Hönig K (2008) The sound of concepts: Four Markers for a link between auditory and conceptual brain systems. J Neurosci 28: 12224-30.

Ruchsow M, Grön G, Kiefer M, Hermle L, Spitzer M, Falkenstein M (2008) Impulsiveness and ERP components in a Go/Nogo task. J Neural Transm 115: 909-15.

Ruchsow M, Grön G, Kiefer M, Buchheim A, Walter H, Martius P, Reiter M, Hermle L, Spitzer M, Ebert D, Falkenstein M (2008) Response inhibition in borderline personality disorder event-related potentials in a Go/Nogo task. J Neural Transm 115: 127-33.

Ruchsow M, Grön G, Kiefer M, Beschoner P, Hermle L, Ebert D, Falkenstein M (2008) Electrophysiological evidence for reduced inhibitory control in depressed patients in partial remission: A Go/Nogo study. Int J Psychophysiol 68: 209-218.

Ruchsow M, Grön G, Spitzer M, Hermle L, Buchheim A, Kiefer M .Electrophysiological evidence for a syntactic but not semantic deficit in patients with major depression. J Psychophysiol.  In press

Sokolov A , Grön G (2008) Die vergessene Säule: Was unser Gedächtnis stärkt. Gedächtniskonsolidierung aus der Sicht der heutigen Hirnforschung. Nervenheilkunde 27: 53-6.

Thielscher A, Kölle M, Neumann H, Spitzer M, Grön G (2008) Texture segmentation in human perception: a combined modeling and fMRI study. Neuroscience 151: 730-6.

Vasic N, Walter H, Höse A, Wolf RC (2008) Gray matter reduction associated with psychopathology and cognitive dysfunction in unipolar depression: A voxel-based morphometry study. J Affect Disorders 109: 107-16.

Vasic N, Lohr C, Steinbrink C, Martin C, Wolf RC (2008) Neural correlates of working memory performance in adolescents and young adults with dyslexia: An event-related, parametric, performance controlled fMRI study. Neuropsychologia 46: 640-8.

Wolf RC, Sambataro F, Vasic N, Schönfeldt-Lecuona C, Ecker D, Landwehrmeyer G (2008) Altered frontostriatal coupling in pre-manifest Huntington's disease: effects of increasing cognitive load. Eur J Neurol 15: 1180-90.

Wolf RC, Höse A, Frasch K, Walter H, Vasic N (2008) Volumetric abnormalities associated with cognitive deficits in patients with schizophrenia. Eur Psychiat 23: 541-8.

Wolf RC, Vasic N, Schönfeldt-Lecuona C, Ecker D, Landwehrmeyer G (2008) Funktionelle Bildgebung kognitiver Prozesse bei Patienten mit Morbus Huntington und präsymptomatischen Mutationsträgern. Nervenarzt 79: 408-20.

cWolf RC, Sambataro F, Vasic N, Schönfeldt-Lecuona C, Ecker D, Landwehrmeyer G (2008) Aberrant connectivity of lateral prefrontal networks in presymptomatic Huntinton's disease. Exp Neurol 213: 137-44.

 

2009

Abler B, Hahlbrock R, Unrath A, Grön G, Kassubek J (2009) At-risk for pathological gambling: imaging neural reward processing under chronic dopamine agonists. Brain 132(Pt 9): 2396-402.

Abler B, Herrnberger B, Grön G, Spitzer M (2009) From uncertainty to reward: BOLD characteristics differentiate signaling pathways. BMC Neurosci 10: 154.

Klöppel S, Henley S, Hobbs N, Wolf RC, Kassubek J, Tabrizi SJ, Frackowiak R (2009) Magnetic resonance imaging of Huntington’s Disease: Preparing for clinical trials. Neuroscience 164: 205-219.
  
Nowak DA, Berner J, Herrnberger B, Kammer T, Grön G, Schönfeldt-Lecuona C (2009) Continuous theta-burst stimulation over the dordsal premotor cortex interferes with associative learning during object lifting. Cortex 45: 473-82.

Plichta MM, Vasic N, Wolf RC, Lesch KP, Brummer D, Jacob C, Fallgatter AJ, Grön G (2009) Neural Hyporesponsiveness and Hyperresponsiveness During Immediate and Delayed Reward Processing in Adult Attention-Deficit/Hyperactivity Disorder. Biol Psychiat 65: 7-14.

Vasic N, Walter H, Sambataro F, Wolf RC (2009) Aberrant functional connectivity of dorsolateral prefrontal and cingulate networks in patients with major depression during working memory processing. Psychol Med 39: 977-87.

Viviani R, Sim EJ, Richter S, Haffer S, Osterfeld N, Thöne J, Beschoner P (2009) Components of variance in brain perfusion and the design of studies of individual differences: the baseline study. Neuroimage 46: 12-22.

Walter H, Ciaramidaro A, Adenzato M, Vasic N, Ardito RB, Erk S, Bara BG (2009) Dysfunction of the social brain in schizophrenia is modulated by intention type: an fMRI study. Soc Cogn Affect Neurosci 4: 166-76.
 
Walter H, Kammerer H, Frasch K, Spitzer M, Abler B (2009) Altered reward functions in patients on atypical antipsychotic medication in line with the revised dopamine hypothesis of schizophrenia. Psychopharmacology 206: 121-32.

Wolf RC, Vasic N, Schönfeldt-Lecuona C, Ecker D, Landwehrmeyer G (2009) Cortical dysfunction in patients with Huntington's disease during working memory performance. Hum Brain Mapp 30: 327-39.

Wolf RC, Plichta MM, Sambataro F, Fallgatter AJ, Jacob C, Lesch KP, Herrmann MJ, Schönfeldt-Lecuona C, Connemann BJ, Grön G, Vasic N (2009) Regional brain activation changes and abnormal functional connectivity of the ventrolateral prefrontal cortex during working memory processing in adults with attention-deficit/hyperactivity disorder. Hum Brain Mapp 30: 2252-2266.

Wolf RC, Vasic N, Sambataro F, Höse A,  Frasch K, Schmid M, Walter H (2009) Temporally anticorrelated brain networks during working memory performance reveal aberrant prefrontal and hippocampal connectivity in patients with schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry 33: 1464-1473.

 

2010

Adolph O, Köster S, Georgieff M, Bäder S, Föhr KJ, Kammer T, Herrnberger B, Grön G (2010) Xenon-induced changes in CNS sensitization to pain. Neuroimage 49: 720-730.

Fladung A-K, Grön G, Grammer K, Herrnberger B, Schilly E, Grasteit S, Wolf RC, Walter H, von Wietersheim JA (2010)  A Neural Signature of Anorexia Nervosa in the Ventral Striatal Reward System. Am J Psychiatry 167: 206-212.

Ulrich M, Jonas C, Grön G (2010) Functional compensation of increasing memory encoding demands in the hippocampus. Neuroreport 21: 59-63.

Videsott G, Herrnberger B, Hoenig K, Schilly E, Grothe J, Wiater W, Spitzer M, Kiefer M (2010) Speaking in multiple languages: neural correlates of language proficiency in multilingual word production. Brain Lang 113: 103-12.

Viviani R, Beschoner P, Lo H, Osterfeld N, Thöne J, Sim EJ (2010) Components of acquisition-to-acquisition variance in continuous arterial spin labelling (CASL) imaging. BMC Neurosci 11: 30.

Viviani R, Sim EJ, Lo H, Beschoner P, Osterfeld N, Maier C, Seeringer A, Godoy A, Rosa A, Comas D, Kirchheiner J (2010) Baseline brain perfusion and the serotonin transporter promoter polymorphism. Biol Psychiatry 67: 317-322.

Wolf RC, Sambataro F, Lohr C, Steinbrink C, Martin C, Vasic N (2010) Functional brain network abnormalities during verbal working memory performance in adolescents and young adults with dyslexia. Neuropsychologia 48: 309-318.

Wolf RC, Walter H, Vasic N (2010) Increasing contextual demand modulates anterior and lateral prefrontal brain regions associated with proactive interference. Int J Neurosci 120: 40-50.

Viviani R, Lo H, Sim EJ, Beschoner P, Stingl JC, Horn AB (2010) The neural substrate of positive bias in spontaneous emotional processing. PLoS One. 5: e15454.

 

2011

Abler B, Seeringer A, Hartmann A, Grön G, Metzger C, Walter M, Stingl J (2011) Neural correlates of antidepressant-related sexual dysfunction: A placebo-controlled fMRI study on healthy males under subchronic paroxetine and bupropion. Neuropsychopharmacol 36: 1837-47.

Cardenas-Morales L, Grön G, Kammer T (2011) Exploring the after-effects of theta burst magnetic stimulation on the human motor cortex: A functional imaging study. Hum Brain Mapp 32: 1948-60.

Einsiedel T, Herzig D, Grön G, Mayer J, Becker C, Gebhard F (2011) Mentales Training beeinflusst Bewegungseinschränkung des ruhiggestellten Handgelenks – eine prospektive Experimentalstudie. Z Orthop Unfall 149: 288-295.

Graf H, Abler B, Freudenmann RW, Beschoner P, Schäffeler E, Spitzer M, Schwab M, Grön G (2011) Neural Correlates of Error Monitoring Modulated by Atomoexetine in Healthy Volunteers. Biol Psychiatry 69: 890-897.

Grön G, Sokolov AN, Jonas c, Roebling R, Spitzer M (2011) Increased resting-state perfusion after repeated encoding is related to later retrieval of declarative associative memories. PloS One 6: e19985.

Hönig K, Müller C, Herrnberger B, Sim EJ, Spitzer M, Ehret G, Kiefer M (2011) Neuroplasticity of semantic representations for musical instruments in professional musicians. Neuroimage 56: 1714-25.

Kassubek J, Abler B, Pinkhardt EH (2011) Neural reward processing under dopamine agonists: Imaging. J Neurol Sci 310: 36-9.

Kessler H, Doyen-Waldecker C, Hofer C, Hoffmann H, Traue HC, Abler B (2011) Neural correlates of the perception of dynamic versus static facial expressions of emotion. Psychosoc Med 8: 1-8.

Kirchheiner J, Seeringer A, Godoy AL, Ohmle B, Maier C, Beschoner P, Sim EJ, Viviani R (2011) CYP2D6 in the brain: genotype effects on resting brain perfusion. Mol Psychiatry 16: 333-341.

Viviani R (2011) Effects of large-scale nonstationarity on parametric maps. A study of rest perfusion CASL data. Neuroimage 54: 2066-78.

Wolf RC, Sambataro F, Vasic N, Schmid M, Thomann PA, Bienentreu SD, Wolf ND (2011) Aberrant connectivity of resting-state networks in borderline personality disorder. J Psychiatry Neurosci 36: 402-411.

Wolf RC, Grön G, Sambataro F, Vasic N, Wolf ND, Thomann PA, Saft C, Landwehrmeyer GB, Orth M (2011) Magnetic resonance perfusion imaging of resting-state cerebral blood flow in preclinical Huntington’s disease. J Cereb Blood Flow Metab 31: 1908-18.

Wolf RC, Sambataro F, Vasic N, Wolf ND, Thomann PA, Landwehrmeyer GB, Orth M (2011) Longitudinal functional magnetic resonance imaging of cognition in preclinical Huntington’s disease. Exp Neurol 231: 214-22.

Wolf RC, Grön G, Sambataro F, Vasic N, Wolf ND, Thomann PA, Saft C, Landwehrmeyer GB, Orth M (2011) Brain activation and functional connectivity in premanifest Huntington’s disease during states of intrinsic and phasic alertness. Hum Brain Mapp 33: 2161-2173.

 

2012

Abler B, Grön G, Hartmann A, Metzger C, Walter M (2012) Modulation of frontostriatal interaction aligns with reduced primary reward processing under serotonergic Drugs. J Neurosci 32: 1329-35.

Kiefer M, Trumpp NM, Herrnberger B, Sim EJ, Hönig K, Pulvermüller F (2012) Dissociating the representation of action- and sound-related concepts in middle temporal cortex. Brain Lang 122: 120-125.

Sosic-Vasic Z, Ulrich M, Ruchsow M, Vasic N, Grön G (2012) The modulating effect of personality traits on neural error monitoring: evidence from event-related fMRI. PloS One 7: e42930.

Viviani R, Abler B, Seeringer A, Stingl JC (2012) Effect of paroxetine and bupropion on human resting brain perfusion: an arterial spin labeling study. Neuroimage 61: 773-9.

Wolf ND, Grön G, Sambataro F, Vasic N, Frasch K, Schmid M, Thomann PA, Wolf RC (2012) Magnetic resonance perfusion imaging of auditory verbal hallucinations in patients with schizophrenia. Schizophr Res. 134: 285-7.

Wolf RC, Sambataro F, Vasic N, Wolf ND, Thomann PA, Saft C, Landwehrmeyer B, Orth M (2012) Default-mode network changes in preclinical Huntington’s disease. Exp Neurol 237: 191-198.

Wolf RC, Thomann PA, Sambataro F, Vasic N, Schmid M, Wolf ND (2012) Orbitofrontal cortex and impulsivity in borderline personality disorder: an MRI study of baseline brain perfusion. Eur Arch Psychiatry Clin Neurosci 262: 677-685

 

2013

Abler B, Kumpfmüller D, Grön G, Walter M, Stingl J, Seeringer A (2013) Neural correlates of erotic stimulation under different levels of female sexual hormones. PlOS One 8: e54447.

Graf H, Abler B, Hartmann A, Metzger CD, Walter M (2013) Modulation of attention network activation under antidepressant agents in healthy subjects. Int J Neuropsychopharmacol 16:1219-1230.

Stingl JC, Brockmöller J, Viviani R (2013) Genetic variability of drug-metabolizing enzymes: the dual impact on psychiatric therapy and regulation of brain function. Mol Psychiatry 18: 273-87.

Trumpp NM, Kliese D, Hönig K, Haarmeier T, Kiefer M (2013) Losing the sound of concepts: Damage to auditory association cortex impairs the processing of soundrelated concepts. Cortex 49: 474-86.

Wolf RC, Thomann PA, Thomann AK, Vasic N, Wolf ND, Landwehrmeyer GB, Orth M (2013) Brain structure in preclinical Huntington’s Disease: A multi-method approach. Neurodegener Dis 12: 13-22.

Bonenberger M, Groschwitz R, Kumpfmüller D, Grön G, Plener P, Abler B (2013) It's all about money: oral contraception alters neural reward processing. Neuroreport 24: 951-55.

Fladung A-K, Schulze UM, Schöll F, Bauer K, Grön G (2013) Role of the ventral striatum in developing anorexia nervosa. Trans Psychiatry 3: e315.

Lernbass B, Grön G, Wolf ND, Abler B (2013) Cigarette smoking modulates medication-associated deficits in a monetary reward task in patients with schizophrenia. Eur Arch Psychiatry Clin Neurosci 263: 509-17.

Müller HP, Grön G, Sprengelmeyer R, Kassubek J, Ludolph A, Hobbs N, Cole J, Roos RA, Duerr A, Tabrizi SJ, Landwehrmeyer GB, Süssmuth SD (2013) Evaluationg multicenter DTI data in Huntington's disease on site specific effects: An expost facto approach. Neuroimage Clin 2: 161-67.

Ulrich M, Hönig K, Grön G, Kiefer M (2013) Brain Activation during Masked and Unmasked Semantic Priming: Commonalities and Differences. J Cogn Neurosci 25: 2216-29.

 

2014

Brückner S, Kammer T (2014) Is theta burst stimulation applied to visual cortex able to modulate peripheral visual acuity? PlosOne 9: e99429.

Cardenas-Morales L, Grön G, Sim E J, Stingl J,  Kammer T (2014) Neural Activation in Humans during a Simple Motor Task Differs between BDNF Polymorphisms. PLoS One 9: e96722.

Freund W, Faust S, Gaser C, Grön G, Birklein F, Wunderlich AP, Müller M, Billich C, Schulze UM (2014) Regionally accentuated reversible brain grey matter reduction in ultra marathon runners detected by voxel-based morphometry. BMC Sports Sci Med Rehabil 6: 4.

Graf H, Walter M, Metzger CD, Abler B (2014) Antidepressant-related sexual dysfunction – Perspectives from neuroimaging. Pharmacol Biochem Behav 121: 138-45.

Herkt D, Tumani V, Grön G, Kammer T, Hofmann A, Abler B (2014) Facilitating Access to Emotions: Neural Signature of EMDR Stimulation. PLoS One 9: e106350.

Kubera KM, Sambataro F, Vasic N, Wolf ND, Frasch K, Hirjak D, Thomann PA, Wolf RC (2014) Source-based morphometry of gray matter volume in patients with schizophrenia who have persistent auditory verbal halluciations. Prog Neuropsychopharmacol Biol Psychiatry 50: 102-9.

Müller HP, Kassubek J, Grön G, Sprengelmeyer R, Ludolph A, Klöppel S, Hobbs N, Roos RA, Dürr A, Tabrizi SJ, Orth M, Süssmuth SD, Landwehrmeyer GB (2014) Impact of the control for corrupted diffusion tensor imaging data in comparison at the group level: an application in Huntington disease. BioMedical Engineering Online 3: 128.

Sambataro F, Wolf ND, Pennuto M, Vasic N, Wolf RC (2014) Revisiting default mode network function in major depression: evidence for disrupted subsystem connectivity. Psychol Med 44: 2041-51.

Sprengelmeyer R, Orth M, Müller HP, Wolf RC, Grön G, Depping MS, Kassubek J, JustoD, Rees EM, Haider S, Cole J, Hobbs N, Roos RA, Dürr A, Tabrizi SJ, Süssmuth SD (2014) The neuroanatomy of subthreshold depressive symptoms in Huntington's disease: a combined diffusior tensor imaging (DTI) and voxel - based morphometry (VBM) study. Psychol Med 44: 1867-78.

Ulrich M, Keller J, Hoenig K, Waller C, Grön G (2014) Neural correlates of experimentally induced flow experiences. Neuroimage 86: 194-202.

Ulrich M, Adams SC, Kiefer M (2014) Flexible Establishment of Functional Brain Networks Supports Attentional Modulation of Unconscious Cogniton. Hum Brain Mapp 35: 5500-16.

Vasic N, Plichta MM, Wolf RC, Fallgatter A J, Sosic-Vasic Z, Grön, G (2014) Reduced Neural Error Signaling in Left Inferior Prefrontal Cortex in Young Adults with ADHD. J Atten Disord 18: 659-70.

Viviani R, Lehmann ML, Stingl JC (2014) Use of Magnetic Resonance Imaging in Pharmacogenomics. Br J Clin Pharmacol 77: 684-94.

Viviani R (2014) Neural correlates of emotion regulation in the ventral prefrontal cortex and the encoding of subjective value and economic utility. Front Psychiatry 5: 123.

Wolf RC, Sambataro F, Vasic N, Wolf ND, Thomann PA, Landwehrmeyer GB, Orth M (2014) Longitudinal task-negative network analyses in preclinical Huntington’s disease. Eur Arch Psychiatry Clin Neurosci 264: 493-505.

Wolf RC, Sambataro F, Vasic N, Baldas EM, Ratheiser I, Landwehrmeyer GB, Depping MS, Thomann PA, Sprengelmeyer R, Süssmuth S, Orth M (2014). Visual system integrity and cognition in early Huntington's disease. Eur J Neurosci 40: 2417-26.

Wolf RC, Huber M, Lepping P, Sambataro F, Depping MS, Karner M, Freudenmann RW (2014) Source-based morphometry reveals distinct patterns of aberrant brain volume in delusional infestation. Prog Neuropsychopharmacol Biol Psychiatry 48: 112-16.

Wolf RC, Sambataro F, Vasic N,  Depping MS, Thomann PA, Landwehrmeyer GB, Süssmuth S, Orth M (2014) Abnormal resting-state connectivity of motor and cognitive networks in early manifest Huntington’s disease. Psychol Med 44: 3341-56.

 

2015

Bonenberger M, Plener PL, Groschwitz RC, Grön G, Abler B (2015) Polymorphism in the µ-opioid receptor gene (OPRM1) modulates neural processing of physical pain, social rejection and error processing. Exp Brain Res 233: 2517-26.

Bonenberger M, Plener PL, Groschwitz RC, Grön G, Abler B (2015) Differential neural processing of unpleasant haptic sensations in somatic and affective partitions of the insula in non-suicidal self-injury (NSSI). Psychiatry Res Neuroimaging 234: 298-304.

Brückner S, Kammer T (2015) High visual demand following theta burst stimulation modulates the effect on visual cortex excitability. Front Hum Neurosci 9: 591. DOI: 10.3389/fnhum.2015.00591.

Depping MS, Wolf ND, Vasic N, Sambataro F,  Thomann PA, Wolf RC (2015) Specificity of abnormal brain volume in major depressive disorder: A comparison with borderline personality disorder. J Affect Dis 174: 650-7.

Graf H, Wiegers M, Metzger CD, Walter M, Grön G, Abler B (2015) Erotic Stimulus Processing under Amisulpride and Reboxetine: A Placebo-Controlled fMRI Study in Healthy Subjects. Int J Neuropsyhopharmacol 18: 1-9.

Ludwig VU, Seitz J, Schönfeldt-Lecuona C, Höse A, Abler B, Hole G, Goebel R, Walter H (2015) The neural correlates of movement intentions: A pilot study comparing hypnotic and simulated paralysis. Conscious Cogn 35: 158-70.

Makwana A, Grön G, Fehr E, Hare TA (2015) A Neural Mechanism of Strategic Social Choice under Sanction-Induced Norm Compliance. eNeuron  2(3)e0066-14.2015 1-8 DOI:http://dx.doi.org/10.1523/ENEURO.0066-14.2015

Messina I, Bianco S, Sambin M, Viviani R (2015) Executive and semantic processes in reappraisal of negative stimuli: insights from a meta-analysis of neuroimaging studies. Front Psychol 6: 956.

Probst-Schendzielorz K, Viviani R, Stingl JC (2015) Effect of Cytochrome P450 polymorphism on the action and metabolism of selective serotonin reuptake inhibitors. Expert Opin Drug Metab Toxicol 11: 1219-32.

Sim EJ, Helbig HB, Graf M, Kiefer M (2015) When Action Observation Facilitates Visual Perception: Activation in Visuo-Motor Areas Contributes to Object Recognition. Cereb Cortex 25: 2907-18.

Stingl J, Viviani R (2015) Polymorphism in CYP2D6 and CYP2C19, members of the cytochrome P450 mixted-function oxidase system, in the metabolism of psychotropic drugs. J Intern Med 277: 167-77.

Straub J, Plener PL, Spröber N, Sprenger L, Kölch MG, Grön G, Abler B (2015) Neural correlates of successful psychotherapy of depression in adolescents. J Affect Disord 183: 239-46.

Ulrich M, Kiefer M, Bongartz W, Grön G, Hönig K (2015) Suggestion-Induced Modulation of Semantic Priming during Functional Magnetic Resonance Imaging. PLoS One 10: e0123686.

Vasic N, Wolf ND, Grön G, Sosic-Vasic Z, Connemann BJ, Sambataro F, von Strombeck A, Lang D, Otte S, Dudek M, Wolf RC (2015) Baseline brain perfusion and brain structure in patients with major depression: a multimodal magnetic resonance imaging study. J Psychiatry Neurosci 40: 412-421.

Wurster CD, Graf H, Ackermann H, Groth K, Kassubek J,  Riecker A (2015). Neural correlates of rate-dependent finger-tapping in Parkinson's disease. Brain Struct Funct 220: 1637-48.

 

2016

Buchheim A, Erk S, George C, Kächele H, Martius P, Pokorny D, Spitzer M, Walter H (2016) Neural Response during the Activation of the Attachment System in Patients with Borderline Personality Disorder: An fMRI Study. Front Hum Neurosci 10 (Article 389).

Depping MS, Wolf ND, Vasic N, Sambataro F, Hirjak D, Thomann PA, Wolf RC (2016) Abnormal cerebellar volume in acute and remitted major depression. Prog Neuropsychopharmacol Biol Psychiatry 71: 97-102.

Groschwitz RC, Plener P, Grön  G, Bonenberger M, Abler B (2016) Differential neural processing of social exclusion in adolescents with non-suicidal self-injury: An fMRI study. Psychiatry Res-Neuroimaging 255: 43-49.

Graf H, Metzger CD, Walter M, Abler B (2016) Serotonergic antidepressants decrease hedonic signals but leave learning signals in the nucleus accumbens unaffected. Neuroreport 27: 18-22.

Hübers A, Kassubek J, Grön G, Gorges M, Aho-Oezhan H, Keller J, Horn H, Neugebauer H, Utter I, Lulé D, Ludolph AC (2016) Pathological laughing and crying in amyotrophic lateral sclerosis is related to frontal cortex function. J Neurol 263: 1788-1795.

Labek K, Viviani R, Gizewski ER, Verius M, Buchheim A (2016) Neural Correlates of the Appraisal of Attachment Scenes in Healthy Controls and Social Cognition - An fMRI Study. Front Hum Neurosci 10 (Article 345).

Messina I, Sambin M, Beschoner P, Viviani R (2016) Changing views of emotion regulation and neurobiological models of the mechanism of action of psychotherapy. Cogn Affect Behav Neurosci 16: 571-87.

Metzger CD, Wiegers M, Walter M, Abler B, Graf H (2016) Local and Global Resting State Activity in the Noradrenergic and Dopaminergic Pathway Modulated by Reboxetine and Amisulpride in Healthy Subjects. Int J Neuropsychopharmacol 19(2): DOI: 10.1093/ijnp/pyv080.

Müller HP, Gorges M, Grön G, Kassubek J, Landwehrmeyer GB, Süssmuth SD, Wolf RC, Orth M (2016) Motor network structure and function are associated with motor performance in Huntington’s disease. J Neurol 263: 539-549.

Müller HP, Turner MR, Grosskreutz J, Abrahams S, Bede P, Govind V, Prudlo J, Ludolph A, Filippi M, Kassubek J (2016) A large-scale multicentre cerebral diffusion tensor imaging study in amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry 87: 570-579.

Ulrich M, Endres F, Kölle MA, Adolph O, Widenhorn-Müller K, Grön G (2016) Glucose modulates food-related salience coding of midbrain neurons in humans. Hum Brain Mapp 37: 4376-4384.

Ulrich M, Kiefer M (2016) The Neural Signature of Subliminal Visumotor Priming: Brain Activity and Functional Connectivity Profiles. Cereb Cortex 26: 2471-2482.

Ulrich M, Keller J, Grön G (2016) Neural signatures of experimentally induced flow experiences identified in a typical fMRI block design with BOLD imaging. Soc Cogn Affect Neurosci 11: 496-507.

Ulrich M, Keller J, Grön G (2016) Dorsal Raphe Nucleus Down-Regulates Medial Prefrontal Cortex during Experience of Flow. Front Behav Neurosci 10 (Article 169).

Ulrich M, Steigleder L, Grön G (2016) Neural Signature of the Food Craving Questionnaire (FCQ)-Trait. Appetite 107: 303-310.

Viviani R (2016) A Digital Atlas of Middle to Large Brain Vessels and Their Relation to Cortical and Subcortical Structures. Front Neuroanat 10: 12. DOI: 10.3389/fnana.2016.00012. eCollection 2016.

 

2017 -

Gorges M, Müller HP, Mayer IMS, Grupe GS, Kammer T, Grön G, Kassubek J, Landwehrmeyer GB, Wolf RC, Orth M (2017) Intact sensory-motor network structure and function in far from onset premanifest Huntington's disease. Sci Rep 7 (Article 43841).

Labek K, Berger S, Buchheim A, Bosch J, Spohrs J, Dommes L, Beschoner P, Stingl J, Viviani R (2017) The iconography of mourning and its neural correlates: A functional neuroimaging study. Soc Cogn Affect Neurosci [Epub ahead of print].

Malejko K, Abler B, Plener P, Straub J (2017) Neural Correlates of Psychotherapeutic Treatment of Post-traumatic Stress Disorder: A Systematic Literature Review. Front Psychiatry 8 (Article 85).

Napolitano G, Stingl J, Schmid M, Viviani R (2017) Predicting CYP2D6 phenotype from resting brain perfusion images by gradient boosting. Psychiatry Res Neuroimaging 259: 16-24.

Sosic-Vasic Z, Abler B, Grön G, Plener P, Straub J (2017) Effects of a brief cognitive behavioural therapy group intervention on baseline brain perfusion in adolescents with major depressive disorder. Neuroreport 28: 348-353.

Straub J, Metzger C, Plener P, Koelch MG, Grön G, Abler B (2017) Successful group psychotherapy of depression in adolescents alters frontolimbic resting-state connectivity. J Affect Disord 209:135-139.

Viviani R, Pracht ED, Brenner D, Beschoner P, Stingl J, Stöcker T (2017) Multimodal MEMPRAGE, FLAIR, and [Formula: see text] Segmentation to Resolve Dura and Vessels from Cortical Gray Matter. Front Neurosci 11 (Article 258).

Viviani R, Stocker T, Stingl JC (2017) Multimodal FLAIR/MPRAGE segmentation of cerebral cortex and cortical myelin. Neuroimage 152:130-141.