The ULMTeC Core Facility for Organoids (CFO) provides services for the establishment and cultivation of organoid models, as well as the testing of clinically relevant substances on these cultures.
Organoids are three-dimensional epithelial structures that mimic the architecture and function of their tissue of origin — in cancer, inflammatory, and healthy conditions alike — offering unprecedented insight into human biology.

The Core Facility develops and applies cutting-edge 3D organoid models that bring human biology closer to the bench. These organoid systems serve as powerful tools to connect experimental research with clinically relevant questions, including the generation of patient-matched organoid and stromal cultures from the same tissue source — thereby accelerating discoveries across cancer biology and precision medicine.

We currently host a living biobank of more than 250 organoid lines derived from over ten tumor indications, including pancreatic, colorectal, and breast cancers, with further tumor entities such as urothelial carcinoma under active establishment.
Our standardized workflows include tissue dissociation, biobanking, automated seeding, matrix-free (apical-out) organoid culture systems, and high-throughput screening — all tailored for both academic and industrial partners.