Cancer represents one of the deadliest diseases of our century. Tumor cells are characterized by the ability to grow uncontrollably, change their shape, acquire invasive properties and to spread through the blood stream to other parts of the body where they form metastases. Our lab is committed to investigate various aspects of tumorigenesis and tumor progression of pancreatic cancer (PDAC) and aims at characterizing the role of crucial signaling pathways controlled by several protein kinases.