Resident, Board Neurology and Psychiatry (Department of  Neurology and Psychiatry, University of Münster FRG)(Prof. G. Brune, Prof. R. Tölle)

Stipend, Deutsche Forschungsgemeinschaft: Institute of Neurotoxicology, Albert Einstein College of Medicine, Bronx, New York (Prof. P.S. Spencer, Prof. H.H. Schaumburg)

Staff, Department of Neurology, University of Münster (Prof. G. Brune)

Habilitation, Faculty of Medicine, University of Münster, C2 Professor of Neurology

Staff Scientist, Visiting Assoc. Prof., Center for Research on Occuputational and Environmental Toxicology, Portland (Oregon)

Staff, Department of Epileptology, University of Bonn (Prof. C.E. Elger)

C3 Professor of Neurology, Vice Chairman, Department of Neurology, Humboldt University Berlin (Prof. K.-M. Einhäupl)

C4 Professor of Neurology, Chair, Department of Neurology, University of Ulm

Chair (elected) Academic Neuroscience Center, University of Ulm

Deputy Chair and Chair (elected), European ALS-MND-Group

Chair (elected) ALS panel of the EFNS and EAN (since 2014, together with Prof. Vincenzo Silani)

Scientific Advisory Board Thierry Latran Foundation

Chair, Scientific Council of Deutsche Stiftung Querschnittlähmung (DSQ)

Chair Scientific Council Deutsche Gesellschaft für Muskelkranke

Scientific Advisory Board Member of the Stifterverband der Schilling-Research-Groups for Translational Neuroscience

Chair (elected), World Federation of Neurology, ALS Research Group

Reviewer for Neuroscience Board of the German Research Foundation (DFG)

Vice Dean of the Medical Faculty of Ulm

>Chair (elected), World Federation of Neurology, ALS Research Group

Delegate of the German Society of Neurology at the World Federation of Neurology

2015 – 2017

Speaker (elected), Clinical Neurosciences Neurowissenschaftliche Gesellschaft (German Society of Neuroscience)

2017 – 2021

Deputy Chair and Chair elected Neurowissenschaftliche Gesellschaft (German Society of Neuroscience)

2017 –

Chair Scientific Advisory Board Thierry Latran Foundation

Månberg A, Skene N, Sanders F, Trusohamn M, Remnestål J, Szczepińska A, Aksoylu IS, Lönnerberg P, Ebarasi L, Wouters S, Lehmann M, Olofsson J, von Gohren Antequera I, Domaniku A, De Schaepdryver M, De Vocht J, Poesen K, Uhlén M, Anink J, Mijnsbergen C, Vergunst-Bosch H, Hübers A, Kläppe U, Rodriguez-Vieitez E, Gilthorpe JD, Hedlund E, Harris RA, Aronica E, Van Damme P, Ludolph AC, Veldink J, Ingre C, Nilsson P, Lewandowski SA. Altered perivascular fibroblast activity precedes ALS disease onset. Nat Med. 2021 Apr;27(4):640-646.

Dorst J, Schuster J, Dreyhaupt J, Witzel S, Weishaupt JH, Kassubek J, Weiland U, Petri S, Meyer T, Grehl T, Hermann A, Jordan B, Grosskreutz J, Zeller D, Boentert M, Schrank B, Prudlo J, Winkler AS, Gorbulev S, Roselli F, Dupuis L, Otto M, Ludolph AC. Effect of high-caloric nutrition on serum neurofilament light chain levels in amyotrophic lateral sclerosis. J Neurol Neurosurg Psych 2020;91(9):1007-1009

Hagenacker T, Wurster CD, Günther R, Schreiber-Katz O, Osmanovic A, Petri S, Weiler M, Ziegler A, Kuttler J, Koch JC, Schneider I, Wunderlich G, Schloss N, Lehmann HC, Cordts I, Deschauer M, Lingor P, Kamm C, Stolte B, Pietruck L, Totzeck A, Kizina K, Mönninghoff C, von Velsen O, Ose C, Reichmann H, Forsting M, Pechmann A, Kirschner J, Ludolph AC, Hermann A, Kleinschnitz C. Nusinersen in adults with 5q spinal muscular atrophy: a non-interventional, multicentre, observational cohort study. Lancet Neurol 2020;19(4):317-325

Ludolph AC, Dorst J, Dreyhaupt J, Weishaupt JH, Kassubek J, Weiland U, Meyer T, Petri S, Hermann A, Emmer A, Grosskreutz J, Grehl T, Zeller D, Boentert M, Schrank B, Prudlo J, Winkler AS, Gorbulev S, Roselli F, Schuster J, Dupuis L; LIPCAL-ALS Study Group. Effect of High-Caloric Nutrition on Survival in Amyotrophic Lateral Sclerosis. Ann Neurol 2020;87(2):206-216

Ludolph AC, Emilian S, Dreyhaupt J, Rosenbohm A, Kraskov A, Lemon RN, Del Tredici K, Braak H. Pattern of paresis in ALS is consistent with the physiology of the corticomotoneuronal projections to different muscle groups. J Neurol Neurosurg Psych 2020;(9):991-998

Lulé DE, Müller HP, Finsel J, Weydt P, Knehr A, Winroth I, Andersen P, Weishaupt J, Uttner I, Kassubek J, Ludolph AC. Deficits in verbal fluency in presymptomatic C9orf72 mutation gene carriers-a developmental disorder. J Neurol Neurosurg Psych 2020;91(11):1195-1200

Miller T, Cudkowicz M, Shaw PJ, Andersen PM, Atassi N, Bucelli RC, Genge A, Glass J, Ladha S, Ludolph AC, Maragakis NJ, McDermott CJ, Pestronk A, Ravits J, Salachas F, Trudell R, Van Damme P, Zinman L, Bennett CF, Lane R, Sandrock A, Runz H, Graham D, Houshyar H, McCampbell A, Nestorov I, Chang I, McNeill M, Fanning L, Fradette S, Ferguson TA. Phase 1-2 Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS. N Engl J Med 2020;383(2):109-119

Oeckl P, Weydt P, Thal DR, Weishaupt JH, Ludolph AC, Otto M. Proteomics in cerebrospinal fluid and spinal cord suggests UCHL1, MAP2 and GPNMB as biomarkers and underpins importance of transcriptional pathways in amyotrophic lateral sclerosis. Acta Neuropathol 2020;139(1):119-134

Ludolph AC, Schuster J, Dorst J, Dupuis L, Dreyhaupt J, Weishaupt JH, Kassubek J, Weiland U, Petri S, Meyer T, Grosskreutz J, Schrank B, Boentert M, Emmer A, Hermann A, Zeller D, Prudlo J, Winkler AS, Grehl T, Heneka MT, Wollebæk Johannesen S, Göricke B; RAS-ALS Study Group. Safety and efficacy of rasagiline as an add-on therapy to riluzole in patients with amyotrophic lateral sclerosis: a randomised, double-blind, parallel-group, placebo-controlled, phase 2 trial. Lancet Neurol 2018;17(8):681-688

Lulé DE, Aho-Özhan HEA, Vázquez C, Weiland U, Weishaupt JH, Otto M, Anderl-Straub S, Semler E, Uttner I, Ludolph AC. Story of the ALS-FTD continuum retold: rather two distinct entities. J Neurol Neurosurg Psych 2019;90(5):586-589